In the present work, we investigated the relationship between mitochondrial function and Ca2+ homeostasis in brain slices obtained from mice that aged normally. In acute …
S Schuchmann, M Luckermann… - Journal of …, 2000 - journals.physiology.org
In hippocampal slices from rats, dialysis with rhodamine-123 (Rh-123) and/or fura-2 via the patch electrode allowed monitoring of mitochondrial potential (ΔΨ) changes and …
Depolarization of neurons promotes Ca2+ influx through voltage-activated channels, raising the intracellular Ca2+ concentration ([Ca2+] i). The consequences of such changes in …
D Murchison, DC Zawieja, WH Griffith - Cell Calcium, 2004 - Elsevier
Alterations of neuronal Ca2+ homeostatic mechanisms could be responsible for many of the cognitive deficits associated with aging in mammals. Mitochondrial participation in Ca2+ …
B Khodorov, V Pinelis, T Storozhevykh… - FEBS …, 1999 - Wiley Online Library
The objective of this study was to evaluate the role of mitochondrial Ca2+ uptake (MCU) in modulation (shaping) of the glutamate (Glu)‐induced changes in neuronal cytoplasmic …
S Kahlert, G Reiser - FEBS letters, 2002 - Wiley Online Library
The influence of cytosolic Ca2+ load and of mitochondrial membrane potential change on mitochondrial morphology was investigated in cultured rat hippocampal astrocytes. The …
SW Leslie, LJ Chandler, EM Barr, RP Farrar - Brain research, 1985 - Elsevier
Synaptosomes were isolated from cerebral cortex of 3-, 18-and 24-month-old male, Fisher 344 rats and 45 Ca 2+ uptake was measured at 1, 3, 5 and 30 s time periods following 65 …
FX Sureda, E Escubedo, C Gabriel… - … : The Journal of the …, 1997 - Wiley Online Library
Mitochondrial membrane potential (MMP) in dissociated rat cerebellar neurons was measured using rhodamine 123 (Rh 123) as fluorescent dye, and flow cytometry. Dye …