Efficacy and tolerability of combination therapy with valsartan plus hydrochlorothiazide compared with amlodipine monotherapy in hypertensive patients with other …

LM Ruilope, E Malacco, Y Khder, A Kandra… - Clinical …, 2005 - Elsevier
BACKGROUND:: Recent antihypertensive treatment guidelines recommend greater use of
combination therapies. OBJECTIVES:: The primary objective of this study was to determine …

Comparison of valsartan/hydrochlorothiazide combination therapy at doses up to 320/25 mg versus monotherapy: a double-blind, placebo-controlled study followed …

JL Pool, R Glazer, M Weinberger, R Alvarado… - Clinical …, 2007 - Elsevier
BACKGROUND:: One third of patients treated for hypertension attain adequate blood
pressure (BP) control, and multidrug regimens are often required. Given the lifelong nature …

Amlodipine/valsartan/hydrochlorothiazide: fixed-dose combination in hypertension

ED Deeks - American journal of cardiovascular drugs, 2009 - Springer
Abstract▲ Amlodipine/valsartan/hydrochlorothiazide (HCTZ) is a fixed-dose combination of
the well established antihypertensive agents amlodipine (a calcium channel antagonist) …

Efficacy and tolerability of valsartan in combination with hydrochlorothiazide in essential hypertension

W Dallas Hall, R Montoro, T Littlejohn, A Jain… - Clinical drug …, 1998 - Springer
Objective: This study compared the efficacy and tolerability of two combination regimens of
valsartan and hydrochlorothiazide (HCTZ) with valsartan monotherapy in patients with …

A multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination versus amlodipine in patients with mild to moderate hypertension

P Palatini, E Malacco, R Fogari, R Carretta… - Journal of …, 2001 - journals.lww.com
A multicenter, randomized double-blind study of valsartan/hy... : Journal of Hypertension A
multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination …

Antihypertensive efficacy and tolerability of two fixed-dose combinations of valsartan and hydrochlorothiazide compared with valsartan monotherapy in patients with …

Y Lacourcière, L Poirier, D Hebert, L Assouline… - Clinical …, 2005 - Elsevier
BACKGROUND:: Combination therapy with at least 2 antihypertensive agents is usually
needed to achieve appropriate blood pressure (BP) control in patients with isolated or …

Real-world clinical experience of amlodipine/valsartan and amlodipine/valsartan/hydrochlorothiazide in hypertension: the EXCITE study

J Sison, SH Assaad-Khalil, R Najem… - … medical research and …, 2014 - Taylor & Francis
Abstract Objective: The EXCITE (clinical EXperienCe of amlodIpine and valsarTan in
hypErtension) study was designed to evaluate the effectiveness, tolerability and adherence …

Cardiovascular outcomes in hypertensive patients: comparing single-agent therapy with combination therapy

MA Weber, S Julius, SE Kjeldsen, Y Jia… - Journal of …, 2012 - journals.lww.com
Objectives: To determine whether blood pressure (BP) control in hypertensive patients
achieved with combination drug therapy provides the same cardiovascular benefits as with …

Amlodipine/valsartan/hydrochlorothiazide triple combination therapy in moderate/severe hypertension: secondary analyses evaluating efficacy and safety

DA Calhoun, NA Crikelair, J Yen, RD Glazer - Advances in therapy, 2009 - Springer
Introduction An 8-week trial of amlodipine/valsartan/hydrochlorothiazide (Aml/Val/HCTZ) for
moderate or severe hypertension demonstrated more-pronounced blood pressure (BP) …

Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with …

JR Benz, HR Black, A Graff, A Reed… - Journal of human …, 1998 - nature.com
Objective: This study compares the antihypertensive efficacy and tolerability of valsartan, a
novel angiotensin II antagonist, given with hydrochlorothiazide (HCTZ) vs placebo or vs …