Neuronal Wiskott-Aldrich Syndrome protein (N-WASP) transmits signals from Cdc42 to the
nucleation of actin filaments by Arp2/3 complex. Although full-length N-WASP is a weak …

The Wiskott-Aldrich syndrome protein (WASP) and its relative neural WASP (N-WASP)
regulate the nucleation of actin filaments through their interaction with the Arp2/3 complex …

We identified a novel adaptor protein that contains a Src homology (SH) 3 domain, SH3
binding proline-rich sequences, and a leucine zipper-like motif and termed this protein …

Proteins of the Wiskott-Aldrich Syndrome protein (WASp) family connect signaling pathways
to the actin polymerization-driven cell motility. The ubiquitous homolog of WASp, N-WASp, is …

Wiskott-Aldrich syndrome protein (WASP) and neural (N)-WASP regulate dynamic actin
structures through the ability of their VCA domains to bind to and stimulate the actin …

The Neuronal Wiskott–Aldrich syndrome protein (N-WASP) has emerged as a central
regulator of the actin cytoskeleton with abilities to integrate multiple upstream signal inputs …

The proteins of the Wiskott-Aldrich syndrome protein (WASP) family are activators of the
ubiquitous actin nucleation factor, the Arp2/3 complex. WASP family proteins contain a C …

Actin polymerization at the cell cortex is thought to provide the driving force for aspects of
cell-shape change and locomotion. To coordinate cellular movements, the initiation of actin …

Protrusion of lamellipodia and filopodia from the cell surface requires that actin polymerize
locally. Actin polymerization is initiated by numerous agonists, including growth factors …

Protein-tyrosine kinases and Rho GTPases regulate many cellular processes, including the
reorganization and dynamics of the actin cytoskeleton. The Wiskott-Aldrich syndrome protein …