Salmonella exploits the host endolysosomal tethering factor HOPS complex to promote its intravacuolar replication

A Sindhwani, SB Arya, H Kaur, D Jagga, A Tuli… - PLoS …, 2017 - journals.plos.org
Salmonella enterica serovar typhimurium extensively remodels the host late endocytic
compartments to establish its vacuolar niche within the host cells conducive for its …

How to do business with lysosomes: Salmonella leads the way

A Tuli, M Sharma - Current opinion in microbiology, 2019 - Elsevier
Pathogens have devised various strategies to alter the host endomembrane system towards
building their replicative niche. This is aptly illustrated by Salmonella Typhimurium, whereby …

The Salmonella Effector PipB2 Affects Late Endosome/Lysosome Distribution to Mediate Sif Extension

LA Knodler, O Steele-Mortimer - Molecular biology of the cell, 2005 - Am Soc Cell Biol
After internalization into mammalian cells, the bacterial pathogen Salmonella enterica
resides within a membrane-bound compartment, the Salmonella-containing vacuole (SCV) …

PLEKHM1 regulates Salmonella-containing vacuole biogenesis and infection

DG McEwan, B Richter, B Claudi, C Wigge, P Wild… - Cell host & …, 2015 - cell.com
The host endolysosomal compartment is often manipulated by intracellular bacterial
pathogens. Salmonella (Salmonella enterica serovar Typhimurium) secrete numerous …

Salmonella SPI1 effector SipA persists after entry and cooperates with a SPI2 effector to regulate phagosome maturation and intracellular replication

LC Brawn, RD Hayward, V Koronakis - Cell host & microbe, 2007 - cell.com
Salmonellae employ two type III secretion systems (T3SSs), SPI1 and SPI2, to deliver
virulence effectors into mammalian cells. SPI1 effectors, including actin-binding SipA, trigger …

Sorting nexin-1 defines an early phase of Salmonella-containing vacuole-remodeling during Salmonella infection

MV Bujny, PA Ewels, S Humphrey… - Journal of cell …, 2008 - journals.biologists.com
Salmonella enterica serovar Typhimurium replicate within host cells in a specialized
membrane-bound compartment, the Salmonella-containing vacuole (SCV). Interaction of …

Salmonella SipA mimics a cognate SNARE for host Syntaxin8 to promote fusion with early endosomes

PK Singh, A Kapoor, RM Lomash, K Kumar… - Journal of Cell …, 2018 - rupress.org
SipA is a major effector of Salmonella, which causes gastroenteritis and enteric fever.
Caspase-3 cleaves SipA into two domains: the C-terminal domain regulates actin …

[HTML][HTML] Salmonella translocated effectors recruit OSBP1 to the phagosome to promote vacuolar membrane integrity

AM Kolodziejek, MA Altura, J Fan, EM Petersen… - Cell Reports, 2019 - cell.com
Intracellular Salmonella use a type III secretion system (TTSS) to translocate effector
proteins across the phagosome membrane and thus promote vacuole membrane tubulation …

The COPII complex and lysosomal VAMP7 determine intracellular Salmonella localization and growth

JC Santos, M Duchateau, J Fredlund… - Cellular …, 2015 - Wiley Online Library
S almonella invades epithelial cells and survives within a membrane‐bound compartment,
the S almonella‐containing vacuole (SCV). We isolated and determined the host protein …

Salmonella‐Containing Vacuoles: Directing Traffic and Nesting to Grow

MA Bakowski, V Braun, JH Brumell - Traffic, 2008 - Wiley Online Library
Salmonella enterica serovar Typhimurium (S. typhimurium) is a gram‐negative facultative
intracellular pathogen that can infect a broad range of mammalian hosts. Following invasion …