Constant infusion of GnRH agonist (GnRH-A) leads to far greater suppression of
spermatogenesis and gonadotropins in the monkey than its intermittent administration. We …

Chronic treatment with agonist analogs of GnRH results in reversible oligospermia i man,
but leads to impotence and decreased libido due to a concomitant fall in serum testosterone …

Constant infusion of gonadotropin-releasing hormone agonist (GnRH-A) in the rhesus
monkey leads to far greater suppression of spermatogenesis than its intermittent …

Superactive analogues of gonadotrophin releasing hormone and testosterone, when
administered together, synergistically inhibit gonadotrophin secretion and spermatogenesis …

Five adult male rhesus monkeys were continuously infused for 56 dayswith 25 μg/day of
GnRH agonist (Wy-40972; Ag) using an implanted osmotic pump. Bioassayable serum …

Synthetic long-acting agonistic analogs of GnRH both stimulate and paradoxically inhibit
gonadotropin secretion in male animals and humans. To characterize the stimulatory and …

To assess its gonadotropin-inhibiting potency in man, three different doses of a GnRH
antagonist ([Ac-D2-Nal1, d4-Cl-Phe2, d3-Pal3, Arg5, d4-p-methoxybenzoyl-2-amino butyric …

We examined the effect of continuous sc infusion of a GnRH agonist (Ag) and testosterone
(T) supplementation on spermatogenesis and the potential fertilizing capacity of sperm in 15 …

Observations that hypophysectomized men demonstrate predictable azoospermia have led
to attempts to suppress gonadotropin secretion with drugs for contraceptive purposes …

GnRH antagonists suppress pituitary and gonadal function by competing with endogenous
GnRH for binding to receptors on pituitary gonadotrophs. We studied the effects of GnRH …