Prolonged duration of gonadotropin inhibition by a third generation GnRH antagonist

JA Leal, RF Williams, DR Danforth… - The Journal of …, 1988 - academic.oup.com
The dose-response effects of a single administration of Nal-Lys-GnRHant (antagonist) on
serum LH and FSH concentrations were compared to the effects of Nal-Glu-GnRHant in …

Hormonal effects of single gonadotropin-releasing hormone antagonist doses in men

F Jockenhövel, S Bhasin, BS Steiner… - The Journal of …, 1988 - academic.oup.com
To assess its gonadotropin-inhibiting potency in man, three different doses of a GnRH
antagonist ([Ac-D2-Nal1, d4-Cl-Phe2, d3-Pal3, Arg5, d4-p-methoxybenzoyl-2-amino butyric …

The stimulatory and down-regulatory effects of a gonadotropin-releasing hormone agonist in man

D HEBER, S BHASIN, B STEINER… - The Journal of …, 1984 - academic.oup.com
Synthetic long-acting agonistic analogs of GnRH both stimulate and paradoxically inhibit
gonadotropin secretion in male animals and humans. To characterize the stimulatory and …

Evidence of differential control of FSH and LH secretion by gonadotropin-releasing hormone (GnRH) from the use of a GnRH antagonist

JE HALL, TD BRODIE, TM BADGER… - The Journal of …, 1988 - academic.oup.com
The differential regulation of immunoactive FSH and LH secretion by endogenous GnRH
was studied using a GnRH antagonist,[Ac-D2Nal1, d4FPhe2, dTrp3, dArg6] GnRH (the NAL …

Marked suppression of gonadotropins and testosterone by an antagonist analog of gonadotropin-releasing hormone in men

W Salameh, S Bhasin, B Steiner, LA McAdams… - Fertility and sterility, 1991 - Elsevier
To study the dose response characteristics of a gonadotropin-releasing hormone (GnRH)
antagonist ([Ac-D 2-Nal 1, D 4-Cl-Phe 2, D 3-Pal 3, Arg 5, dGlu 6 (AA), d-Ala 10] GnRH; Nal …

GnRH agonists

ED Schriock - Clinical obstetrics and gynecology, 1989 - journals.lww.com
University of Tennessee Memphis, Tennessee onadotropin releasing hormone (Gn-RH),
also referred to as LH-RH (luteinizing hormone releasing hormone) or LRF (luteinizing …

Gonadotrophin-releasing hormone (GnRH) overcomes GnRH antagonist-induced suppression of LH secretion in primates

GR Marshall, F Bint Akhtar… - Journal of …, 1986 - joe.bioscientifica.com
If the suppressive effects of gonadotrophin-releasing hormone (GnRH) antagonists on
gonadotrophin secretion are mediated through GnRH-receptor occupancy alone, it should …

Applications for GnRH antagonists

DL Blithe - Trends in Endocrinology & Metabolism, 2001 - cell.com
Applications for GnRH antagonists: Trends in Endocrinology & Metabolism Skip to Main
Content Advertisement Trends in Endocrinology & Metabolism This journal offers authors two …

Suppression of bioactive and immunoreactive follicle-stimulating hormone and luteinizing hormone levels by a potent gonadotropin-releasing hormone antagonist …

JF Mortola, M Sathanandan, S Pavlou, KD Dahl… - Fertility and sterility, 1989 - Elsevier
Dose-dependent gonadotropin suppression by a potent gonadotropin-releasing hormone
(GnRH) antagonist, Nal 1 Glu 6 ([Ac-D 2 Nal 1, D 4 ClPhe 2, D 3 Pal 3, Arg 5, DGlu (AA) 6 …

Differential regulation of luteinizing hormone, follicle-stimulating hormone, and free α-subunit secretion from the gonadotrope by gonadotropin-releasing hormone …

JE Hall, RW Whitcomb, JE Rivier… - The Journal of …, 1990 - academic.oup.com
To examine the differential regulation of glycoprotein hormone secretion from the
gonadotrope by GnRH, the Nal-Glu GnRH antagonist was administered to euthyroid women …