Lipid extraction is a critical step in sample preparation of lipidomics studies. Biphasic liquid-
liquid extraction protocol with methyl tert-butyl ether (MTBE)/methanol (MeOH) as organic …

A key element of successful lipidomics analysis is a sufficient extraction of lipid molecules
typically by two-phase systems such as chloroform-based Bligh and Dyer (B&D). However …

Lipidomics is a rapidly developing field in modern biomedical research. While LC-MS
systems are able to detect most of the known lipid classes in a biological matrix, there is no …

An unbiased sample preparation free of interferents (ie, competing analytes, detergents,
plastics) is critical to any lipid MS workflow. Here we present a novel three-phase lipid …

Blood plasma has gained protagonism in lipidomics studies due to its availability,
uncomplicated collection and preparation, and informative readout of physiological status. At …

Extraction of the lipid fraction is a key part of acquiring lipidomics data. High-throughput
lipidomics, the extraction of samples in 96w plates that are then run on 96 or 384w plates …

The goal of this research was to find the most comprehensive lipid extraction of blood
plasma, while also providing adequate aqueous preparation for metabolite analysis …

In order to profile the lipidome for untargeted lipidomics applications, analysis by ultra-high
performance liquid chromatography–high resolution mass spectrometry (UHPLC-HRMS) …

Given the chemical diversity of lipids and their biological relevance, suitable methods for
lipid profiling and quantification are demanded to reduce sample complexity and analysis …

The use of dried blood spots has increased in research and clinical settings recently,
particularly in field studies and screening, but comprehensive acyl-specific lipidomic …