Background Granulomatosis with polyangiitis (GPA) is a rare systemic autoimmune disease.
Smaller sample size and complex nature of the disease pathogenesis has made it …

Objectives To examine the association of previously identified autoimmune disease
susceptibility loci with granulomatosis with polyangiitis (GPA, formerly known as Wegener's …

Objective To examine the association of previously identified autoimmune disease
susceptibility loci with granulomatosis with polyangiitis (Wegener's)(GPA), and to determine …

Granulomatosis with polyangiitis (GPA) is a severe autoimmune disease and one of the
small vessel anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides. Although …

Granulomatosis with polyangiitis (GPA) previously known as Wegener's granulomatosis
(WG) is a rare rheumatic disease affecting subjects of all ages. Prevalence and incidence of …

Objective To identify genetic determinants of granulomatosis with polyangiitis
(Wegener's)(GPA). Methods We carried out a genome‐wide association study (GWAS) of …

Objective. Granulomatosis with polyangiitis (GPA) is a rare autoimmune systemic vasculitis
considered to result from the interaction of environmental factors with a genetically …

Granulomatosis with polyangiitis (GPA) is a rare systemic autoimmune disease. Major
contributions of HLA genes have been reported; however, HLA typing-based diagnosis or …

The aetiology of granulomatosis with polyangiitis (GPA) remains unclear. There is likely a
complex interplay between environmental triggers and genetic predisposition. Early …

Objective To analyse the role of the PTPN22 and CSK genes, previously associated with
autoimmunity, in the predisposition and clinical phenotypes of giant cell arteritis (GCA) …