Nanoparticle-based strategies for cancer immunotherapy and immunodiagnostics

AM Grimaldi, M Incoronato, M Salvatore… - Nanomedicine, 2017 - Taylor & Francis
Although recent successes in clinical trials are strengthening research focused on cancer
immunology, the poor immunogenicity and off-target side effects of immunotherapeutics …

Nanoparticle‐based nanomedicines to promote cancer immunotherapy: recent advances and future directions

J Liu, R Zhang, ZP Xu - Small, 2019 - Wiley Online Library
Cancer immunotherapy is a promising cancer terminator by directing the patient's own
immune system in the fight against this challenging disorder. Despite the monumental …

Nanoparticulate delivery of cancer cell membrane elicits multiantigenic antitumor immunity

AV Kroll, RH Fang, Y Jiang, J Zhou, X Wei… - Advanced …, 2017 - Wiley Online Library
Anticancer vaccines train the body's own immune system to recognize and eliminate
malignant cells based on differential antigen expression. While conceptually attractive …

Nanoparticle-based immunotherapy for cancer

K Shao, S Singha, X Clemente-Casares, S Tsai… - ACS …, 2015 - ACS Publications
The design of nanovaccines capable of triggering effective antitumor immunity requires an
understanding of how the immune system senses and responds to threats, including …

Cancer immunotherapy: nanodelivery approaches for immune cell targeting and tracking

J Conniot, JM Silva, JG Fernandes, LC Silva… - Frontiers in …, 2014 - frontiersin.org
Cancer is one of the most common diseases afflicting people globally. New therapeutic
approaches are needed due to the complexity of cancer as a disease. Many current …

Cancer nanoimmunotherapy using advanced pharmaceutical nanotechnology

W Li, H Wei, H Li, J Gao, SS Feng, Y Guo - Nanomedicine, 2014 - Taylor & Francis
Immunotherapy is a promising option for cancer treatment that might cure cancer with fewer
side effects by primarily activating the host's immune system. However, the effect of …

Nanoparticles: properties and applications in cancer immunotherapy

A Iscaro, NF Howard, M Muthana - Current Pharmaceutical …, 2019 - ingentaconnect.com
Background: Tumours are no longer regarded as isolated masses of aberrantly proliferating
epithelial cells. Rather, their properties depend on complex interactions between epithelial …

Immunomodulatory nanoparticles activate cytotoxic T cells for enhancement of the effect of cancer immunotherapy

K Wells, T Liu, L Zhu, L Yang - Nanoscale, 2024 - pubs.rsc.org
Cancer immunotherapy represents a promising targeted treatment by leveraging the
patient's immune system or adoptive transfer of active immune cells to selectively eliminate …

Engineered nanoparticles for cancer vaccination and immunotherapy

ME Aikins, C Xu, JJ Moon - Accounts of chemical research, 2020 - ACS Publications
Conspectus The immune system has evolved over time to protect the host from foreign
microorganisms. Activation of the immune system is predicated on a distinction between self …

Emerging nanotechnologies for cancer immunotherapy

S Shukla, NF Steinmetz - Experimental biology and …, 2016 - journals.sagepub.com
Founded on the growing insight into the complex cancer-immune system interactions,
adjuvant immunotherapies are rapidly emerging and being adapted for the treatment of …