Introduction Noninvasive ventilation (NIV) improves survival among patients with
hypercapnic respiratory failure in hospital, but evidence for its use in domiciliary settings is …

Despite the fact that metanalyses and clinical guidelines do not recommend the routine use
of domiciliary non-invasive ventilation (NIV) for patients diagnosed with severe stable …

Background: Uncertainty remains around the benefit of home non-invasive ventilation (NIV)
for stable chronic obstructive pulmonary disease (COPD) patients and those with a recent …

Background In chronic obstructive pulmonary disease, the prognosis for patients who have
survived an episode of acute hypercapnic respiratory failure due to an exacerbation is poor …

Background Chronic obstructive pulmonary disease (COPD) is a chronic progressive lung
disease characterised by non-reversible airflow obstruction. Exacerbations are a key cause …

Long-term or home mechanical noninvasive ventilation (Home-NIV) has become a well-
established form of therapy over the last few decades for chronic hypercapnic COPD …

Background Not all hypercapnic COPD patients benefit from home noninvasive ventilation
(NIV), and mechanisms through which NIV improves clinical outcomes remain uncertain. We …

Background Home noninvasive ventilation (NIV) has been increasingly used in stable
chronic obstructive pulmonary disease (COPD) with chronic hypercapnic respiratory failure …

Background Chronic obstructive pulmonary disease (COPD) is a chronic disease associated
with recurring exacerbations, which influence morbidity and mortality for the patient, while …

Background Patients with chronic hypercapnic respiratory failure due to chronic obstructive
pulmonary disease (COPD) are very likely to develop acute exacerbations. Non-invasive …