NSAID therapy effects on healing of bone, tendon, and the enthesis

B Su, JP O'Connor - Journal of applied physiology, 2013 - journals.physiology.org
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used for the treatment of
skeletal injuries. The ability of NSAIDs to reduce pain and inflammation is well-established …

Effect of non-steroidal anti-inflammatory drugs on bone healing

J Cottrell, JP O'Connor - Pharmaceuticals, 2010 - mdpi.com
Nonspecific and COX-2 selective nonsteroidal anti-inflammatory drugs (NSAIDs) function by
inhibiting the cyclooxygenase isoenzymes and effectively reduce pain and inflammation …

Nonsteroidal anti-inflammatory drugs (NSAIDs) and their effect on musculoskeletal soft-tissue healing: a scoping review

N Ghosh, OO Kolade, E Shontz, Y Rosenthal… - JBJS …, 2019 - journals.lww.com
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) are being increasingly
employed as a part of multimodal non-opioid strategies to treat postoperative pain. In the …

The effect of nonsteroidal anti-inflammatory drugs on tissue healing

MR Chen, JL Dragoo - Knee Surgery, Sports Traumatology, Arthroscopy, 2013 - Springer
Abstract Purpose Non-selective (NSAIDs) and selective (COX-2) nonsteroidal anti-
inflammatory drugs are commonly used for their analgesic and anti-inflammatory effects …

The mechanisms of the inhibitory effects of nonsteroidal anti‐inflammatory drugs on bone healing: a concise review

AT Harder, YH An - The Journal of Clinical Pharmacology, 2003 - Wiley Online Library
Nonsteroidal anti‐inflammatory drug (NSAID) use continues to expand at a remarkable rate
due both to the broad spectrum of clinical applications for these medications and to the …

[PDF][PDF] Do steroids, conventional non-steroidal anti-inflammatory drugs and selective Cox-2 inhibitors adversely affect fracture healing

LA Boursinos, T Karachalios, L Poultsides… - J Musculoskelet …, 2009 - ismni.org
Non-steroidal anti-inflammatory drugs (NSAIDs) are among the most commonly used drugs
worldwide. They are prescribed for orthopaedic conditions such as osteoarthritis, soft-tissue …

Positives and negatives of nonsteroidal anti-inflammatory drugs in bone healing: the effects of these drugs on bone repair

B Lisowska, D Kosson, K Domaracka - Drug design, development …, 2018 - Taylor & Francis
Tissue damage following injury triggers the processes of coagulation, inflammation and
healing. In tissues surrounding the bone, the result of the healing process is a scar, while …

Effects of cyclooxygenase inhibition on bone, tendon, and ligament healing

ZA Radi, NK Khan - Inflammation Research, 2005 - Springer
Cyclooxygenases (COX-1 and COX-2) catalyze the conversion of arachidonic acid to
prostaglandins (PGs). PGs play a significant role in bone metabolism in health and disease …

The effect of nonsteroidal anti-inflammatory drug administration on acute phase fracture-healing: a review

AP Kurmis, TP Kurmis, JX O'Brien, T Dalén - JBJS, 2012 - journals.lww.com
Background: The analgesic efficacy of nonsteroidal anti-inflammatory drugs (NSAIDs) is well
established, and these agents often form an integral part of posttraumatic pain management …

[HTML][HTML] The effect of non-steroidal anti-inflammatory drugs on tendon-to-bone healing: a systematic review with subgroup meta-analysis

KR Duchman, DB Lemmex, SH Patel… - The Iowa orthopaedic …, 2019 - ncbi.nlm.nih.gov
Background: There is some concern that non-steroidal anti-inflammatory drugs (NSAIDs)
may impair the healing of certain musculoskeletal tissues. However, the effect of NSAIDs on …