Effect of the phospholipase A2 inhibitor Varespladib, and its synergism with crotalic antivenom, on the neuromuscular blockade induced by Crotalus durissus terrificus …
The venom of the South American rattlesnake Crotalus durissus terrificus causes an
irreversible neuromuscular blockade in isolated preparations due to action of the …
irreversible neuromuscular blockade in isolated preparations due to action of the …
Anti-sera raised in rabbits against crotoxin and phospholipase A2 from Crotalus durissus cascavella venom neutralize the neurotoxicity of the venom and crotoxin
DG Beghini, S Hernandez-Oliveira… - Toxicon, 2004 - Elsevier
Crotoxin, the principal neurotoxin in venom of the South American rattlesnakes Crotalus
durissus terrificus and Crotalus durissus cascavella, contains a basic phospholipase A2 …
durissus terrificus and Crotalus durissus cascavella, contains a basic phospholipase A2 …
Ability of rabbit antiserum against crotapotin to neutralize the neurotoxic, myotoxic and phospholipase A2 activities of crotoxin from Crotalus durissus cascavella snake …
DG Beghini, DCS Damico, MA da Cruz-Höfling… - Toxicology in vitro, 2008 - Elsevier
The toxicity of crotoxin, the major toxin of Crotalus durissus terrificus (South American
rattlesnake) venom, is mediated by its basic phospholipase A2 (PLA2) subunit. This PLA2 is …
rattlesnake) venom, is mediated by its basic phospholipase A2 (PLA2) subunit. This PLA2 is …
Varespladib (LY315920) prevents neuromuscular blockage and myotoxicity induced by crotoxin on mouse neuromuscular preparations
FV Maciel, ÊKR Pinto, NMV Souza, TAG de Abreu… - Toxicon, 2021 - Elsevier
Varespladib (LY315920) is a synthetic phospholipase A 2 (PLA 2) inhibitor that has been
demonstrating antiophidic potential against snake venoms that present PLA 2 neurotoxins …
demonstrating antiophidic potential against snake venoms that present PLA 2 neurotoxins …
Studies on the specificity of CNF, a phospholipase A2 inhibitor isolated from the blood plasma of the South American rattlesnake (Crotalus durissus terrificus). I …
CL Fortes-Dias, MLD Jannotti, FJL Franco… - Toxicon, 1999 - Elsevier
A phospholipase A2 inhibitor has been previously purified and cloned from the blood
plasma of the South American rattlesnake, Crotalus durissus terrificus. This inhibitor, named …
plasma of the South American rattlesnake, Crotalus durissus terrificus. This inhibitor, named …
Neuromuscular paralysis by the basic phospholipase A2 subunit of crotoxin from Crotalus durissus terrificus snake venom needs its acid chaperone to concurrently …
WLG Cavalcante, JB Noronha-Matos… - Toxicology and applied …, 2017 - Elsevier
Background and purpose Crotoxin (CTX), a heterodimeric phospholipase A 2 (PLA 2)
neurotoxin from Crotalus durissus terrificus snake venom, promotes irreversible blockade of …
neurotoxin from Crotalus durissus terrificus snake venom, promotes irreversible blockade of …
[HTML][HTML] Rabbit IgG antibodies against phosphilipase A~ 2 from Crotalus durissus terrificus neutralyze the lethal activity of the venom
Abstract Crotalus durissus terrificus (Cdt.)(South American rattlesnake) venom possesses
myotoxic and neurotoxic activities, both of which are also expressed by crotoxin, the …
myotoxic and neurotoxic activities, both of which are also expressed by crotoxin, the …
Immunochemical analysis of a snake venom phospholipase A2 neurotoxin, crotoxin, with monoclonal antibodies
V Choumet, G Faure, A Robbe-Vincent, B Saliou… - Molecular …, 1992 - Elsevier
Crotoxin is the major neurotoxic component of the venom of the South American rattlesnake,
Crotalus durissus terrificus. The crotoxin molecule is composed of two subunits: a basic and …
Crotalus durissus terrificus. The crotoxin molecule is composed of two subunits: a basic and …
Cross-neutralization of the neurotoxicity of Crotalus durissus terrificus and Bothrops jararacussu venoms by antisera against crotoxin and phospholipase A2 from …
DG Beghini, MA da Cruz-Höfling, P Randazzo-Moura… - Toxicon, 2005 - Elsevier
We have previously demonstrated that rabbit antisera raised against crotoxin from Crotalus
durissus cascavella venom (cdc-crotoxin) and its PLA2 (cdc-PLA2) neutralized the …
durissus cascavella venom (cdc-crotoxin) and its PLA2 (cdc-PLA2) neutralized the …
Neutralization of edema, hemorrhage and myonecrosis induced by North American crotalid venoms in simulated first-aid treatments
J Evans, CL Ownby - Toxicon, 1999 - Elsevier
Venoms of the broad-banded copperhead (Agkistrodon contortrix laticinctus, ACL) and the
prairie rattlesnake (Crotalus viridis viridis, CVV), like other crotalid venoms, cause severe …
prairie rattlesnake (Crotalus viridis viridis, CVV), like other crotalid venoms, cause severe …