Vascular injury triggers two intertwined processes, platelet deposition and coagulation, and
can lead to the formation of an intravascular clot (thrombus) that may grow to occlude the …

The body's response to vascular injury involves two intertwined processes: platelet
aggregation and coagulation. Platelet aggregation is a predominantly physical process …

In the last decade numerous mathematical models have been formulated to investigate
specific components of the clotting system such as the tissue factor pathway of coagulation …

Hemostatic thrombi formed after a penetrating injury have a heterogeneous architecture in
which a core of highly activated, densely packed platelets is covered by a shell of less …

Thrombosis is a life-threatening clinical condition characterized by the obstruction of blood
flow in a vessel due to the formation of a large thrombus. The pathogenesis of thrombosis is …

The formation of wall-adherent platelet aggregates is a critical process in arterial thrombosis.
A growing aggregate experiences frictional drag forces exerted on it by fluid moving over or …

A comprehensive understanding of thrombus formation as a physicochemical process that
has evolved to protect the integrity of the human vasculature is critical to our ability to predict …

The paper presents a mathematical analysis of the contributions of flow and mass transport
to a single reactive event at a blood vessel wall. The intent is to prepare the ground for a …

An extended multiscale model is introduced for studying the formation of platelet thrombi in
blood vessels. The model describes the interplay between viscous, incompressible blood …

A two-dimensional multiscale model is introduced for studying formation of a thrombus (clot)
in a blood vessel. It involves components for modelling viscous, incompressible blood …