Stimuli-responsive drug delivery systems are gaining importance in personalized medicine
to deliver therapeutic doses in response to disease-specific stimulation. Pancreas-mimicking …

Diabetes is a chronic disease affecting over 400 million people worldwide. Inadequate
production of insulin due to loss of beta cells or insulin resistance within the body …

To date, very limited work has been done on convenient and active control of insulin
release. Herein, we report an electro-responsive insulin delivery system based on thiolated …

Achieving persistent glycemic control in a painless and convenient way is the ultimate goal
of diabetes management. Herein, an “enzyme‐free” polymeric microneedle (MN)‐array …

Microneedle (MN) technology, which can transdermally deliver insulin in a noninvasive
manner, offers a promising way to replace subcutaneous self-injection for diabetes …

Microneedles (MNs) have attracted great interest as a drug delivery alternative to
subcutaneous injections for treating diabetes mellitus. We report MNs prepared from …

Insulin is the peptide hormone used to treat the diabetes patient. The hormone is normally
taken by injection. The transdermal drug delivery system (TDDS) is an alternative route. The …

Silk fibroin (SF) has attracted much attention due to its high, tunable mechanical strength
and excellent biocompatibility. Imparting the ability to respond to external stimuli can further …

Silk fibroin has widely been used in biomedical applications for its excellent biocompatibility,
degradability, and mechanical properties. Microneedles are a suitable method for …

This study aimed to develop a silk fibroin (SF)-film for the treatment of chronic diabetic
wounds. Silk fibroin was purified through a newly developed heating degumming (HD) …