A wide variety of disorders, medications, physical factors, and trauma can alter testicular function and reproductive function in men as they age. There are no precise age limits for …
GV Frajese, MU De Martino, E Calcagni… - Journal of …, 2005 - europepmc.org
The quest for eternal youth has been prevalent in civilised societies in many cultures for many centuries. Preventing or deferring the disabilities and morbidities associated with …
LJ Gooren - Asian Journal of Andrology, 2010 - ncbi.nlm.nih.gov
Many signs of aging, such as sexual dysfunction, visceral obesity, impaired bone and muscle strength, bear a close resemblance to features of hypogonadism in younger men …
S Bhasin, RJ Valderrábano, T Gagliano-Jucá - Endotext [Internet], 2022 - ncbi.nlm.nih.gov
In male mammals, changes at all levels of the hypothalamic-pituitary-testicular axis, including alterations in the GnRH pulse generator, gonadotropin secretion, and testicular …
A Vermeulen - The Aging Male, 1998 - Taylor & Francis
Aging in men is accompanied by a gradual decline of all physiologcal functions, involving the heart, lungs, kidneys, liver and brain as well as the endocrine system. The …
C Rolf, E Nieschlag - Experimental and clinical endocrinology & …, 2001 - thieme-connect.com
The changes of reproductive functions, fertility and genetic risks of ageing females have been investigated relatively intensively. The state of knowledge about endocrine and …
Practice Committee of the American Society for … - Fertility and …, 2006 - Elsevier
Although guidelines for androgen replacement therapy for older men have been developed by several groups, the data to support treatment are based on the results of only a small …
E Wespes, CC Schulman - International Journal of Impotence …, 2002 - nature.com
A progressive decrease in androgen production is common in aging men. The physiological causes for this phenomenon seem to be multifactorial. The magnitude of the decline in …
B Lunenfeld - Asian journal of andrology, 2001 - europepmc.org
The prolongation of life expectancy and the drastic reduction of fertility rate are the primary cause of an aging world. It is projected that the elderly (above 65) will increase within the …