Introduction: sickle cell disease (SCD) is a hereditary red blood cell disorder of public health
importance globally with Nigeria the epicenter zone in Africa. There is a paucity of …

Background Africa has the highest burden of Sickle cell disease (SCD) but there are few
large, systematic studies providing reliable descriptions of the disease spectrum. Tanzania …

Background: An estimate of 250,000 children are born annually with sickle cell disease
(SCD) worldwide and 75%–85% of the affected children are born in Africa; where mortality …

Background/objective Sickle cell disease (SCD) is a monogenic disease with multiple
phenotypic expressions. Previous studies describing SCD clinical phenotypes in Nigeria …

Background: The clinical phenotypes of children with sickle cell disease (SCD) are poorly
described in many sub-Saharan countries including Nigeria. Objectives: The objective was …

Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy,
characterized by painful episodes, anemia, high risk of infection, and other acute and …

Sickle cell disease (SCD) is one of the most common life-threatening monogenic disorders
affecting millions of people worldwide. The disease has a high prevalence in malaria …

Background. South Africa has a low incidence of sickle cell disease (SCD). However, its
demographics are changing because of immigration from sub-Saharan African countries …

Sickle cell disease (SCD) exhibits itself in a broad spectrum of clinical behaviour ranging
from a mild disease to an incapacitating condition. In this study, we have attempted to …

Sickle cell anemia (SCA) is the commonest severe monogenic disorders of humans. The
disease has been highly characterized in high‐income countries but not in sub‐Saharan …