A variety of experimental studies have demonstrated the neuroprotective effects of
melatonin, based on its antioxidant activity. In a prospective randomized study, the effects of …

The pineal hormone melatonin is a highly efficient physiological scavenger of free radicals
involved in secondary brain damage. A variety of experimental studies have demonstrated a …

The pineal hormone melatonin has recently been shown to exert neuroprotective activity in a
variety of experimental neuropathologies in which free radicals are involved. This …

Numerous studies showed that melatonin, a free radical scavenger, is neuroprotective. In
this study, we investigated the effect of pinealectomy and administration of exogenous …

Abstract Background and Study Aims: Melatonin is an important antioxidant agent with a
protective role in the prevention of oxidative stress. We designed an experimental study …

The purpose of this study was to evaluate the effect of melatonin on oxidative stress
occurring in the brain after routine lobectomy neurosurgery procedures. Different …

Since free radicals play a role in the mechanisms of brain injury after hemorrhagic stroke,
the effect of melatonin (a potent antioxidant and free-radical scavenger) on outcomes was …

An enormous amount of data has been published in recent years demonstrating melatonin's
defensive role against toxic free radicals. In the present study, we examined the role of …

Head trauma causes two kinds of injury in the neural tissue. One is the primary injury which
occurs at the time of impact. The other one is a secondary injury and is a progressive …

OBJECTIVES: Melatonin, the major secretory product of the pineal gland, is known as an
effective antioxidant and neuroprotector. Its neuroprotective actions and mechanisms have …