Recent advances in analytical strategies for mass spectrometry-based lipidomics

T Xu, C Hu, Q Xuan, G Xu - Analytica chimica acta, 2020 - Elsevier
Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Lipidomics: techniques, applications, and outcomes related to biomedical sciences

K Yang, X Han - Trends in biochemical sciences, 2016 - cell.com
Lipidomics is a newly emerged discipline that studies cellular lipids on a large scale based
on analytical chemistry principles and technological tools, particularly mass spectrometry …

[HTML][HTML] Recent advances towards mass spectrometry-based clinical lipidomics

S Salihovic, S Lamichane, T Hyötyläinen… - Current opinion in …, 2023 - Elsevier
The objective of this review is to provide a comprehensive summary of the latest
methodological advancements and emerging patterns in utilizing lipidomics in clinical …

Recent advances of chromatography and mass spectrometry in lipidomics

M Li, Z Zhou, H Nie, Y Bai, H Liu - Analytical and bioanalytical chemistry, 2011 - Springer
Lipidomics, as a novel branch of metabolomics, which is aimed at comprehensive analysis
of lipids and their biological roles with respect to health and diseases, has attracted …

Analytical strategies in lipidomics and applications in disease biomarker discovery

C Hu, R van der Heijden, M Wang… - … of Chromatography B, 2009 - Elsevier
Lipidomics is a lipid-targeted metabolomics approach aiming at comprehensive analysis of
lipids in biological systems. Recently, lipid profiling, or so-called lipidomics research, has …

Analytical methods in lipidomics and their applications

M Li, L Yang, Y Bai, H Liu - Analytical chemistry, 2014 - ACS Publications
As a branch of metabolomics, lipidomics is aimed at full analysis of lipid species and their
biological roles with respect to health and diseases and has attracted increasing attention of …

Chemical derivatization strategy for mass spectrometry‐based lipidomics

F Xia, JB Wan - Mass Spectrometry Reviews, 2023 - Wiley Online Library
Lipids, serving as the structural components of cellular membranes, energy storage, and
signaling molecules, play the essential and multiple roles in biological functions of …

[HTML][HTML] Recent advances in expanding the coverage of the lipidome

S Tumanov, JJ Kamphorst - Current opinion in biotechnology, 2017 - Elsevier
Highlights•The extreme diversity of the lipidome poses a significant analytical challenge.•A
variety of mass spectrometry-based approaches exist for the analysis of lipids.•Combining …

Chemical derivatization and ultrahigh resolution and accurate mass spectrometry strategies for “shotgun” lipidome analysis

E Ryan, GE Reid - Accounts of Chemical Research, 2016 - ACS Publications
Conspectus Lipids play critical structural and functional roles in the regulation of cellular
homeostasis, and it is increasingly recognized that the disruption of lipid metabolism or …

Applications of mass spectrometry-based targeted and non-targeted lipidomics

HC Lee, T Yokomizo - Biochemical and biophysical research …, 2018 - Elsevier
Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid
metabolic pathways involved in many (patho) physiological events. Targeted and non …