Innate immune activation is crucial in defense against invading pathogens, including
recognition by pattern recognition receptors, such as scavenger receptors. The scavenger …

Scavenger receptors were originally identified by their ability to recognize and to remove
modified lipoproteins; however, it is now appreciated that they carry out a striking range of …

Apoptotic cells are considered to be a major source for autoantigens in autoimmune
diseases such as systemic lupus erythematosus (SLE). In agreement with this, defective …

Scavenger receptors were originally defined by their ability to bind and internalize modified
lipoproteins. Macrophages express at least six structurally different cell surface receptors for …

Scavenger receptors are a highly diverse superfamily of proteins which are grouped by their
inherent ability to bind and internalize a wide array of structurally diverse ligands which can …

Macrophages are able to recognise and internalise apoptotic and foreign cells from the
tissue microenvironment and, where pertinent, initiate inflammation and macrophage …

Scavenger receptors (SR) are expressed by myeloid cells (macrophages and dendritic cells)
and certain endothelial cells. They play an important role in uptake and clearance of effete …

Accumulating evidence indicates that atherosclerosis is a chronic inflammatory disease. The
key innate immune cells that are involved in the pathogenesis of atherosclerosis are …

Scavenger receptors represent a large family of structurally unrelated distinct gene products,
expressed by myeloid and selected endothelial cells and able to recognise modified low …

B cell acquisition and presentation of specific autoantigens (auto-Ags) are thought to play an
important and complex role in autoimmunity development. We previously identified …