Aliskiren prevents the toxic effects of peritoneal dialysis fluids during chronic dialysis in rats

J Perez-Martinez, FC Pérez-Martínez, B Carrion… - PloS one, 2012 - journals.plos.org
The benefits of long-term peritoneal dialysis (PD) in patients with end-stage renal failure are
short-lived due to structural and functional changes in the peritoneal membrane. In this …

A mice model of chlorhexidine gluconate-induced peritoneal damage

MY Chang, HH Wang, LH Chen, J Gao… - JoVE (Journal of …, 2022 - jove.com
Peritoneal fibrosis is an important complication of peritoneal dialysis (PD). To investigate
and address this problem, an appropriate animal model of PD is required. The present …

Contribution of lactate buffer, glucose and glucose degradation products to peritoneal injury in vivo

M Zareie, LHP Hekking, AGA Welten… - Nephrology Dialysis …, 2003 - academic.oup.com
Background. Long-term peritoneal dialysis (PD) is associated with the development of
functional and structural alterations of the peritoneal membrane. In this study, we …

Pharmacologic targets and peritoneal membrane remodeling

K Farhat, AWD Stavenuiter… - Peritoneal Dialysis …, 2014 - journals.sagepub.com
Peritoneal dialysis (PD) is associated with functional and structural changes of the
peritoneal membrane, also known as peritoneal remodeling. The peritoneal membrane is …

Induction of chronic kidney failure in a long-term peritoneal exposure model in the rat: effects on functional and structural peritoneal alterations

F Vrtovsnik, AM Coester… - Peritoneal dialysis …, 2010 - journals.sagepub.com
Background A long-term peritoneal exposure model has been developed in Wistar rats.
Chronic daily exposure to 3.86% glucose based, lactate buffered, conventional dialysis …

[HTML][HTML] Reactive oxygen species amplify protein kinase C signaling in high glucose-induced fibronectin expression by human peritoneal mesothelial cells

HB Lee, MR Yu, JS Song, H Ha - Kidney international, 2004 - Elsevier
Reactive oxygen species amplify protein kinase C signaling in high glucose-induced
fibronectin expression by human peritoneal mesothelial cells. Background We previously …

Peritoneal inflammation and fibrosis in C‐reactive protein transgenic mice undergoing peritoneal dialysis solution treatment

PYK Poon, HY Lan, BCH Kwan, XR Huang… - …, 2017 - Wiley Online Library
Aim C‐reactive protein (CRP) is a mediator of systemic inflammation. Peritoneal dialysis
(PD) is known to cause peritoneal inflammation and fibrosis. We compare the degree of …

Peritoneal dialysis fluid induces p38-dependent inflammation in human mesothelial cells

A Riesenhuber, K Kratochwill… - Peritoneal dialysis …, 2011 - journals.sagepub.com
Background Noninfectious upregulation of proinflammatory pathways in mesothelial cells
may represent an integral part of their stress response upon exposure to peritoneal dialysis …

Tamoxifen attenuates dialysate-induced peritoneal fibrosis by inhibiting GSK-3β/β-catenin axis activation

P Yan, H Tang, X Chen, S Ji, W Jin, J Zhang… - Bioscience …, 2018 - portlandpress.com
Peritoneal fibrosis is a severe complication arising from long-term peritoneal dialysis (PD).
Tamoxifen (Tamo) has been clinically proven effective in a series of fibrotic diseases, such …

Effect of high glucose concentration on the synthesis of monocyte chemoattractant protein-1 in human peritoneal mesothelial cells: involvement of protein kinase C

B Haslinger, S Mandl-Weber, A Sellmayer, SR Lederer… - Nephron, 2001 - karger.com
Human peritoneal mesothelial cells (HMC) contribute to the activation and control of
inflammatory processes in the peritoneum by their potential to produce various inflammatory …