Background. Continuous ambulatory peritoneal dialysis (CAPD) is a major treatment
modality for end-stage renal failure. The peritoneal membrane exhibits pathological …

Abstract Background. High-glucose (HG) content of dialysate accelerated peritoneal fibrosis.
We investigated in vitro mechanisms and the in vivo potential of pentoxifylline (PTX) to …

Peritoneal membrane pathology limits long-term peritoneal dialysis (PD). Here, we tested
whether JAK/STAT signaling is implicated and if its attenuation might be salutary. In cultured …

Long-term exposure to peritoneal dialysis fluid induces morphological alterations, including
angiogenesis, leading to a loss of ultrafiltration (UF) capacity. We discuss the effect of …

Preservation of peritoneal membrane (PM) is essential for long‐term survival in peritoneal
dialysis (PD). Continuous presence of PD fluids (PDF) in the peritoneal cavity generates …

Peritoneal dialysis (PD) and prolonged exposure to PD fluids (PDF) induce peritoneal
membrane (PM) fibrosis and hypervascularity, leading to functional PM degeneration. 2 …

During peritoneal dialysis (PD), exposure of the peritoneal membrane to nonphysiologic
solutions causes inflammation, ultimately leading to altered structure and function …

Background. Peritonitis is a common and severe complication of peritoneal dialysis (PD).
Although TGF-β is a key mediator in peritoneal fibrosis with chronic PD, its role in acute …

Background: Peritoneal mesothelial cell (PMC) plays a key role in the process of peritoneal
fibrosis. Epithelial–mesenchymal transition (EMT) of PMCs is an important mechanism of …

A growing body of evidence indicates that epithelial-mesenchymal transition (EMT) of
human peritoneal mesothelial cells (HPMC) may play an important role in the development …