Six patients with advanced prostatic carcinoma were treated with tamoxifen (2× 20 mg daily)
for up to 3 months before orchiectomy. Blood samples for gonadotropin, sex steroid, and …

Abstract The short‐term (6‐day) endocrine effects of tamoxifen and testolactone were
investigated in men with prostatic carcinoma. Tamoxifen treatment (20 mg/day) did not affect …

Androgen (AR) and progesterone (PR) receptors were measured in resected prostate
tissues of patients with benign prostatic hypertrophy. One group of patients received an anti …

The in-vitro metabolism of testosterone in benign and malignant prostatic tissue was
examined and distinct quantitative differences between the two types of specimens were …

The short-term effects of the administration of estradiol on testicular steroid production were
assessed by measuring the serum concentrations of testosterone, and a number of its …

A group of 19 patients with advanced (Stage D) prostate cancer were treated with one of
three dose levels of the anti‐estrogen tamoxifen, 10 mg (3 patients), 20 mg (8 patients), or …

Patients with advanced prostatic carcinoma who had received minimal or no prior therapy
were treated with tamoxifen citrate in escalating doses from 10 to 50 mg orally twice a day …

Plasma kinetics, in vivo uptake, and intraprostatic metabolism of 3 H testosterone was
investigated in 9 patients with advanced carcinoma of the prostate. The metabolic effect of …

In 36 men with prostatic cancer, the following findings were obtained: intravenous
administration of 12.0 g diethylstilboestrol diphosphate (DSDP) induced a relatively slight …

Alterations in the metabolism of testosterone (T) and dihydrotestosterone (DHT) induced by
diethylstilbestrol (DES) or medroxyprogesterone acetate (MPA) could account for the …