Cognitive differences between early-and late-onset Alzheimer's disease

EA Licht, AM McMurtray, RE Saul… - American Journal of …, 2007 - journals.sagepub.com
Although neuropathologic studies showed that early-onset Alzheimer's disease (EAD) and
“senile dementia” were indistinguishable, clinical studies suggested that EAD and late-onset …

Early onset Alzheimer's disease is associated with a distinct neuropsychological profile

LL Smits, YAL Pijnenburg… - Journal of …, 2012 - content.iospress.com
Alzheimer's disease (AD) in younger patients is associated with a higher prevalence of
atypical symptoms. We examined neuropsychological performance according to age-at …

Early-onset Alzheimer's disease is associated with greater pathologic burden

GA Marshall, LA Fairbanks, S Tekin… - Journal of geriatric …, 2007 - journals.sagepub.com
Two subtypes of Alzheimer's disease (AD) have been commonly identified: early-and late-
onset forms. Previous studies suggest that early-onset AD patients have more neuritic …

Cognitive decline in prodromal Alzheimer disease and mild cognitive impairment

RS Wilson, SE Leurgans, PA Boyle… - Archives of …, 2011 - jamanetwork.com
Objective To characterize the course of cognitive decline during the prodromal phase of
Alzheimer disease. Design Longitudinal cohort study with up to 16 years of observation …

Preclinical Alzheimer disease: neuropsychological test performance 1.5 to 8 years prior to onset

J Saxton, OL Lopez, G Ratcliff, C Dulberg, LP Fried… - Neurology, 2004 - AAN Enterprises
Objective: To determine if individuals ultimately diagnosed with Alzheimer disease (AD)
exhibited evidence of cognitive impairment on neuropsychological tests administered …

Memory decline: the boundary between aging and age-related disease.

MS Albert - Annals of Neurology, 2002 - psycnet.apa.org
Discusses changes in memory associated with aging and the boundary between aging and
Alzheimer's disease (AD). It is noted that there is considerable evidence that normal aging is …

Cognitive decline in Alzheimer's disease: a longitudinal investigation of risk factors for accelerated decline

L Teri, SM McCurry, SD Edland… - The Journals of …, 1995 - academic.oup.com
Abstract Background.—Although Alzheimer's disease (AD) is a progressive degenerative
condition, there is great intra-and inter-individual variability in rates of cognitive decline …

Aβ and cognitive change: Examining the preclinical and prodromal stages of Alzheimer's disease

YY Lim, P Maruff, RH Pietrzak, KA Ellis, D Darby… - Alzheimer's & …, 2014 - Elsevier
Background High β-amyloid (Aβ) is associated with faster memory decline in healthy
individuals and adults with mild cognitive impairment (MCI). However, longer prospective …

Age, Alzheimer's disease and dementia in the Baltimore Longitudinal Study of Ageing

D Dolan, J Troncoso, SM Resnick, BJ Crain… - Brain, 2010 - academic.oup.com
Recent studies suggest that dementia in the most elderly (90 years of age and above) is only
modestly related to Alzheimer's disease pathology. This raises the possibility that other, as …

Cognitive deficits in the early stages of Alzheimer's disease

M Storandt - Current Directions in Psychological Science, 2008 - journals.sagepub.com
Evidence from longitudinal, experimental, and neuroimaging studies converge to indicate
that psychological functions other than episodic memory are affected very early in the course …