Sickle cell disease (SCD) is the most common clinically significant hemoglobinopathy,
characterized by painful episodes, anemia, high risk of infection, and other acute and …

Background Africa has the highest burden of Sickle cell disease (SCD) but there are few
large, systematic studies providing reliable descriptions of the disease spectrum. Tanzania …

Sickle cell disease (SCD) is one of the most prevalent genetic conditions in sub-Saharan
Africa. It is a chronic, lifelong disease often characterized by severe pain. However, SCD has …

Background Sickle cell disease (SCD) is a severe hereditary form of anemia that contributes
between 50% and 80% of under-five mortality in Africa. Eleven thousand babies are born …

Sickle cell disease (SCD) is one of the most common monogenetic diseases worldwide.
Although there have been some advances in the management of SCD in high-income …

Background/objective Sickle cell disease (SCD) is a monogenic disease with multiple
phenotypic expressions. Previous studies describing SCD clinical phenotypes in Nigeria …

Introduction: sickle cell disease (SCD) is a hereditary red blood cell disorder of public health
importance globally with Nigeria the epicenter zone in Africa. There is a paucity of …

In Africa, sickle cell disease (SCD) is a major public health problem with over 200,000
babies born per year. In Ghana, approximately 15,000 (2%) of Ghanaian newborns are …

Sickle cell disease (SCD) is the most prevalent genetic disease in sub-Saharan Africa and
an estimated 240,000 children are born with SCD each year (Piel et al., 2013). Similar to …

Sickle cell disease is caused by an abnormality of the β-globin gene and is characterised by
sickling of the red blood cells. Globally, sub-Saharan African countries share the highest …