Expediting disulfiram assays through a systematic analytical quality by design approach
An Analytical Quality by Design (AQbD) approach is presented, aiming at the development
and validation of an HPLC method for the quantification of disulfiram and copper …
and validation of an HPLC method for the quantification of disulfiram and copper …
Analytical Quality by Design (AQbD) as a multiaddressable platform for co-encapsulating drug assays
The current study describes the application of an Analytical Quality by Design (AQbD)
approach for the selection and optimization of a reversed-phase high performance liquid …
approach for the selection and optimization of a reversed-phase high performance liquid …
A state of the art in analytical quality-by-design and perspectives in characterization of nano-enabled medicinal products
Abstract Quality-by-Design (QbD) guidance is a risk-based and proactive approach to drug
development proposed in the early 2000s and now widely used in the pharmaceutical field …
development proposed in the early 2000s and now widely used in the pharmaceutical field …
Piperazine-tuned NBD-based colorimetric and fluorescent turn-off probes for hydrogen sulfide
The piperazine ring is a very important factor in governing molecular structure to generate
the special properties of a compound. New NBD-based fluorescent probes 1–3 were …
the special properties of a compound. New NBD-based fluorescent probes 1–3 were …
A highly selective colorimetric chemodosimeter for fast and quantitative detection of hydrogen sulfide
Y Zhao, X Zhu, H Kan, W Wang, B Zhu, B Du, X Zhang - Analyst, 2012 - pubs.rsc.org
Based on the fact that hydrogen sulfide (H2S) possesses the smallest steric hindrance
among thiols and the SH− group adds faster to an electron-poor CC double bond, we …
among thiols and the SH− group adds faster to an electron-poor CC double bond, we …
Dual-functional turn-on fluorescent probe for discriminative sulfite and sulfide detection via organic/aqueous ratio tuning and its application in real samples
CC Su, KR Kim, JI Hong - Dyes and Pigments, 2022 - Elsevier
Sulfite and sulfide are substances commonly present in food, biological and industrial
processes. While excess amounts of these anions can elicit physiological disorders in …
processes. While excess amounts of these anions can elicit physiological disorders in …
Using enhanced development tools offered by analytical Quality by Design to support switching of a quality control method
P Simeoni, M Deissler, R Bienert… - Biotechnology and …, 2023 - Wiley Online Library
Abstract Quality by Design (QbD) principles play an increasingly important role in the
pharmaceutical industry. Here, we used an analytical QbD (AQbD) approach to develop a …
pharmaceutical industry. Here, we used an analytical QbD (AQbD) approach to develop a …
Introduction to analytical quality by design
Analytical development is considered as an integral part of the pharmaceutical product life-
cycle, where establishment of an effective, cost-effective, robust, sensitive, and specific …
cycle, where establishment of an effective, cost-effective, robust, sensitive, and specific …
Recent applications of analytical quality-by-design methodology for chromatographic analysis: A review
DT Xuan, HMT Nguyen, VD Hoang - Chemometrics and Intelligent …, 2024 - Elsevier
ABSTRACT Analytical Quality-by-Design (AQbD) represents a systematic methodology for
method development. The pharmaceutical and biopharmaceutical industries have …
method development. The pharmaceutical and biopharmaceutical industries have …
Drilling into “Quality by Design” approach for analytical methods
L Chiarentin, C Gonçalves, C Augusto… - Critical Reviews in …, 2024 - Taylor & Francis
The need for consistency in analytical method development reinforces the dependence of
pharmaceutical product development and manufacturing on robust analytical data. The …
pharmaceutical product development and manufacturing on robust analytical data. The …