The outdoor use of organisms modified with gene drives—emerging biotechnologies of
biased inheritance—could further human well-being and biodiversity conservation, yet also …

Synthetic gene drives raise ethical, ecological, and legal questions that are sometimes
difficult to grasp. What is clear, however, is that the power to directly alter not just a singular …

Vigilantes are members of a self-appointed group of citizens who undertake law
enforcement in their community without legal authority, typically because the legal agencies …

Highlights•Genetic modification and gene drives can help conserve and restore
biodiversity.•'Conservationist synthetic biology'pose environmental risks and social …

Gene drive technology is an emerging biotechnology with the potential to address some of
the most intractable global biodiversity conservation issues. Scientists are exploring …

This chapter overviews the types, purposes, and potential impacts of gene drive organisms
(GDOs) and discusses challenges with foreseeing and assessing these impacts prior to their …

The bioethical debate about using gene drives to alter or eradicate wild populations has
focused mostly on issues concerning short-term risk assessment and management …

The prospect of using genetic methods to target vector, parasite, and reservoir species offers
tremendous potential benefits to public health, but the use of genome editing to alter the …

Gene drives are genetic modifications designed for rapidly diffusing traits throughout a target
population. They are currently being proposed as biological control agents to combat, for …

Environmental releases of gene edited (GEdOs) and gene drive organisms (GDOs) will
likely occur under conditions of high uncertainty and in complex socioecological systems …