Prevention of calcification of bioprosthetic heart valve leaflets by Ca2+ diphosphonate pretreatment
TP Johnston, FJ Schoen, RJ Levy - Journal of pharmaceutical …, 1988 - Wiley Online Library
Calcification frequently causes failure of bioprosthetic heart valves (BHV) fabricated from
glutaraldehyde‐pretreated porcine aortic valve or bovine pericardium. Systemic …
glutaraldehyde‐pretreated porcine aortic valve or bovine pericardium. Systemic …
Controlled release of diphosphonate to inhibit bioprosthetic heart valve calcification: dose-response and mechanistic studies
Calcification is the Principal cause of the clinical faliure of bioprosthetic heart valves (BHV)
fabricated from glutaraldehy de-treated porcine valves or bovine pericardium. This study …
fabricated from glutaraldehy de-treated porcine valves or bovine pericardium. This study …
Controlled release of 1-hydroxyethylidene diphosphonate: in vitro assessment and effects on bioprosthetic calcification in sheep tricuspid valve replacements
TP Johnston, EL Bove, SF Bolling, JA Boyd… - International journal of …, 1989 - Elsevier
Calcification (CALC) is the most frequent cause of the clinical failure of bioprosthetic valves
(BHV's). Controlled-release (paravalvar) administration of the anticalcification agent …
(BHV's). Controlled-release (paravalvar) administration of the anticalcification agent …
Prevention of leaflet calcification of bioprosthetic heart valves with diphosphonate injection therapy: experimental studies of optimal dosages and therapeutic durations
RJ Levy, FJ Schoen, SA Lund, MS Smith - The Journal of Thoracic and …, 1987 - Elsevier
Ethanehydroxydiphosphonate therapy was studied for prevention of calcification of
bioprosthetic heart valve cusps (from glutaraldehyde-preserved porcine aortic valves) …
bioprosthetic heart valve cusps (from glutaraldehyde-preserved porcine aortic valves) …
Controlled release of ethanehydroxy diphosphonate from polyurethane reservoirs to inhibit calcification of bovine pericardium used in bioprosthetic heart valves
TP Johnston, JA Boyd, BL Ciesliga, FJ Schoen… - International journal of …, 1990 - Elsevier
Calcification (CALC) of bioprosthetic heart valves (BHVs) fabricated from either
glutaraldehyde-pretreated bovine pericardial tissue or porcine aortic valves is the most …
glutaraldehyde-pretreated bovine pericardial tissue or porcine aortic valves is the most …
Controlled-release drug delivery of diphosphonates to inhibit bioprosthetic heart valve calcification: release rate modulation with silicone matrices via drug solubility …
G Golomb, M Dixon, MS Smith, FJ Schoen… - Journal of …, 1987 - Elsevier
Calcification (CALC) is the most frequent cause of the clinical failure of bioprosthetic heart
valves (BHV) fabricated from glutaraldehyde pretreated porcine aortic valves or bovine …
valves (BHV) fabricated from glutaraldehyde pretreated porcine aortic valves or bovine …
Inhibition of bioprosthetic heart valve calcification with aminodiphosphonate covalently bound to residual aldehyde groups
CL Webb, JJ Benedict, FJ Schoen, JA Linden… - The Annals of thoracic …, 1988 - Elsevier
Calcification is the principal mode of failure of bioprosthetic heart valves (BPHV) fabricated
from glutaraldehyde-pretreated porcine aortic valves or bovine pericardium. Covalent …
from glutaraldehyde-pretreated porcine aortic valves or bovine pericardium. Covalent …
Inhibition of calcification of bioprosthetic heart valves by local controlled-release diphosphonate
RJ Levy, J Wolfrum, FJ Schoen, MA Hawley, SA Lund… - Science, 1985 - science.org
Bioprostheses fabricated from porcine aortic valves are widely used to replace diseased
heart valves. Calcification is the principal cause of the clinical failure of these devices. In the …
heart valves. Calcification is the principal cause of the clinical failure of these devices. In the …
LOCAL CONTROLLED–RELEASE OF DIPHOSPHONATES FROM ETHYLENEVINYLACETATE MATRICES PREVENTS BIOPROSTHETIC HEART VALVE …
RJ Levy, G Golomb, J Wolfrum, SA Lund… - ASAIO …, 1985 - journals.lww.com
MATERIALS AND METHODS Chemicals and Supplies. Glutaraldehyde was obtained as an
8% aqueous solution from Polysciences (Warrington, PA). Ethylene vinylacetate (EVA)(40 …
8% aqueous solution from Polysciences (Warrington, PA). Ethylene vinylacetate (EVA)(40 …
Inhibition by diphosphonate compounds of calcification of porcine bioprosthetic heart valve cusps implanted subcutaneously in rats.
Calcification limits the long-term success of heart valve bioprostheses fabricated from
glutaraldehyde cross-linked porcine aortic valves. The pathophysiology of calcification of …
glutaraldehyde cross-linked porcine aortic valves. The pathophysiology of calcification of …
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