Efficacy and Safety of Apremilast in Systemic-and Biologic-Naive Patients With Moderate Plaque Psoriasis: 52-Week Results of UNVEIL.

J Bagel, M Lebwohl, JM Jackson, R Chen… - Journal of drugs in …, 2018 - europepmc.org
BACKGROUND: Many patients with moderate plaque psoriasis are undertreated despite
broadening treatment options. In the phase IV UNVEIL study, oral apremilast demonstrated …

Efficacy and safety of apremilast in patients with moderate plaque psoriasis with lower BSA: week 16 results from the UNVEIL study

B Strober, J Bagel, M Lebwohl… - Journal of drugs in …, 2017 - pubmed.ncbi.nlm.nih.gov
INTRODUCTION: Many options are available for patients with moderate to severe plaque
psoriasis. Patients with moderate disease, however, are often undertreated and do not …

Efficacy and safety of apremilast in patients with mild-to-moderate plaque psoriasis: Results of a phase 3, multicenter, randomized, double-blind, placebo-controlled …

LS Gold, K Papp, D Pariser, L Green, N Bhatia… - Journal of the American …, 2022 - Elsevier
Background Patients with mild-to-moderate psoriasis may have substantial quality-of-life
impairment. Objective To evaluate apremilast 30 mg twice daily for mild-to-moderate …

[HTML][HTML] Long-term safety and tolerability of apremilast in patients with psoriasis: Pooled safety analysis for≥ 156 weeks from 2 phase 3, randomized, controlled trials …

J Crowley, D Thaçi, P Joly, K Peris, KA Papp… - Journal of the american …, 2017 - Elsevier
Background Randomized, controlled trials demonstrated efficacy and safety of apremilast for
moderate-to-severe plaque psoriasis and psoriatic arthritis. Objective Assess long-term …

Efficacy and safety of apremilast monotherapy for moderate to severe psoriasis: retrospective study

A Ighani, JR Georgakopoulos, LL Zhou… - Journal of …, 2018 - journals.sagepub.com
Background: Apremilast is a new oral drug for the treatment of moderate to severe plaque
psoriasis that reduces inflammation by inhibiting phosphodiesterase 4. Its efficacy and safety …

Real-World Clinical Experience With Apremilast in a Large US Retrospective Cohort Study of Patients With Moderate to Severe Plaque Psoriasis.

A Armstrong, E Levi - Journal of Drugs in Dermatology: JDD, 2017 - europepmc.org
OBJECTIVE: To examine real-world use and patient outcomes with apremilast, an oral
PDE4 inhibitor, in the dermatology practice set-ting for treatment of patients with moderate to …

[HTML][HTML] Apremilast mechanism of efficacy in systemic-naive patients with moderate plaque psoriasis: pharmacodynamic results from the UNVEIL study

B Strober, A Alikhan, B Lockshin, R Shi, J Cirulli… - Journal of …, 2019 - Elsevier
Background Pharmacodynamic (PD) subanalyses of clinical trials in patients with moderate
to severe psoriasis demonstrated the efficacy of apremilast correlated with reductions in …

Long‐term efficacy and safety of apremilast in the treatment of plaques psoriasis: A real‐world, single‐center experience

G Radi, A Campanati, F Diotallevi… - Dermatologic …, 2021 - Wiley Online Library
Apremilast is a small molecule approved for the treatment of plaques psoriasis and adult
psoriatic arthritis. Pivotal studies have demonstrated short and long term efficacy and safety …

The efficacy and safety of apremilast, etanercept and placebo in patients with moderate‐to‐severe plaque psoriasis: 52‐week results from a phase IIIb, randomized …

K Reich, M Gooderham, L Green… - Journal of the …, 2017 - Wiley Online Library
Background Apremilast, an oral, small‐molecule phosphodiesterase 4 inhibitor, has
demonstrated efficacy in patients with moderate‐to‐severe psoriasis. Objective Evaluate …

Long-term effectiveness and drug survival of apremilast in treating psoriasis: a real-world experience

J Distel, S Cazzaniga, SM Seyed Jafari, V Emelianov… - Dermatology, 2022 - karger.com
Background: Apremilast is an oral phosphodiesterase 4 (PDE4) inhibitor used for the
treatment of moderate to severe psoriasis. Long-term data on the effectiveness and drug …