Differential regulation of luteinizing hormone, follicle-stimulating hormone, and free α-subunit secretion from the gonadotrope by gonadotropin-releasing hormone …

JE Hall, RW Whitcomb, JE Rivier… - The Journal of …, 1990 - academic.oup.com
To examine the differential regulation of glycoprotein hormone secretion from the
gonadotrope by GnRH, the Nal-Glu GnRH antagonist was administered to euthyroid women …

Evidence of differential control of FSH and LH secretion by gonadotropin-releasing hormone (GnRH) from the use of a GnRH antagonist

JE HALL, TD BRODIE, TM BADGER… - The Journal of …, 1988 - academic.oup.com
The differential regulation of immunoactive FSH and LH secretion by endogenous GnRH
was studied using a GnRH antagonist,[Ac-D2Nal1, d4FPhe2, dTrp3, dArg6] GnRH (the NAL …

Changes in gonadotropin and α-subunit secretion after a single administration of gonadotropin-releasing hormone antagonist in adult males

N Lahlou, S Delivet, CW Bardin, M Roger, IM Spitz… - Fertility and sterility, 1990 - Elsevier
The suppressive effect of the gonadotropin-releasing hormone (GnRH) antagonist NalGlu
([Ac-D2Nal1, D4ClPhe2, D3Pal3, Arg5, D-4-p-methoxybenzoyl-2-aminobutyric acid6 …

Marked suppression of gonadotropins and testosterone by an antagonist analog of gonadotropin-releasing hormone in men

W Salameh, S Bhasin, B Steiner, LA McAdams… - Fertility and sterility, 1991 - Elsevier
To study the dose response characteristics of a gonadotropin-releasing hormone (GnRH)
antagonist ([Ac-D 2-Nal 1, D 4-Cl-Phe 2, D 3-Pal 3, Arg 5, dGlu 6 (AA), d-Ala 10] GnRH; Nal …

Hormonal effects of single gonadotropin-releasing hormone antagonist doses in men

F Jockenhövel, S Bhasin, BS Steiner… - The Journal of …, 1988 - academic.oup.com
To assess its gonadotropin-inhibiting potency in man, three different doses of a GnRH
antagonist ([Ac-D2-Nal1, d4-Cl-Phe2, d3-Pal3, Arg5, d4-p-methoxybenzoyl-2-amino butyric …

Suppression of bioactive and immunoreactive follicle-stimulating hormone and luteinizing hormone levels by a potent gonadotropin-releasing hormone antagonist …

JF Mortola, M Sathanandan, S Pavlou, KD Dahl… - Fertility and sterility, 1989 - Elsevier
Dose-dependent gonadotropin suppression by a potent gonadotropin-releasing hormone
(GnRH) antagonist, Nal 1 Glu 6 ([Ac-D 2 Nal 1, D 4 ClPhe 2, D 3 Pal 3, Arg 5, DGlu (AA) 6 …

Administration of low dose pulsatile gonadotropin-releasing hormone (GnRH) to GnRH-deficient men regulates free α-subunit secretion

DI SPRATT, WW CHIN, EC RIDGWAYS… - The Journal of …, 1986 - academic.oup.com
Although pharmacological doses of GnRH and TRH stimulate free α-subunit (α-subunit)
secretion from the pituitary, little is known about the pattern and control of asubunit release …

The dynamics of gonadotropin inhibition in women induced by an antagonistic analog of gonadotropin-releasing hormone

NS Cetel, J Rivier, W Vale… - The Journal of Clinical …, 1983 - academic.oup.com
The inhibitory effect of a GnRH antagonist,[AC-Δ2-Pro1, pFd-Phe2, d-Trp36] GnRH (4F-
Antag), on gonadotropin secretion was determined by four sequential studies in five …

The stimulatory and down-regulatory effects of a gonadotropin-releasing hormone agonist in man

D HEBER, S BHASIN, B STEINER… - The Journal of …, 1984 - academic.oup.com
Synthetic long-acting agonistic analogs of GnRH both stimulate and paradoxically inhibit
gonadotropin secretion in male animals and humans. To characterize the stimulatory and …

Effects of chronic GnRH analogue administration on gonadotrophin and α‐subunit secretion in post‐menopausal women

DS Oppenheim, H Bikkal, WF Crowley Jr… - Clinical …, 1992 - Wiley Online Library
OBJECTIVE To investigate in detail the regulation of LH, FSH, and α‐subunit secretion by a
GnRH agonist analogue under physiological conditions of gonadotrophin elevation …