Use of N-Acetylcysteine at high doses as an oral treatment for patients hospitalized with COVID-19
JL Izquierdo, JB Soriano, Y González… - Science …, 2022 - journals.sagepub.com
Infection by SARS-CoV-2 causing coronavirus disease 2019 (COVID-19) can be associated
with serious and life-threatening conditions, including acute respiratory distress syndrome …
with serious and life-threatening conditions, including acute respiratory distress syndrome …
N-acetyl-cysteine reduces the risk for mechanical ventilation and mortality in patients with COVID-19 pneumonia: a two-center retrospective cohort study
SF Assimakopoulos, D Aretha, D Komninos… - Infectious …, 2021 - Taylor & Francis
Background N-acetyl-cysteine (NAC) has been previously shown to exert beneficial effects
in diverse respiratory diseases, through antioxidant and anti-inflammatory actions. Our aim …
in diverse respiratory diseases, through antioxidant and anti-inflammatory actions. Our aim …
[HTML][HTML] N-acetylcysteine for prevention and treatment of COVID-19: Current state of evidence and future directions
JL Izquierdo-Alonso, S Pérez-Rial, CG Rivera… - Journal of infection and …, 2022 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection causes
coronavirus disease 2019 (COVID-19) and can be associated with serious complications …
coronavirus disease 2019 (COVID-19) and can be associated with serious complications …
A pilot study on intravenous N-Acetylcysteine treatment in patients with mild-to-moderate COVID19-associated acute respiratory distress syndrome
Background We designed this single-centre clinical trial to assess the potential benefits of N-
Acetylcysteine (NAC) in patients with COVID19-associated acute respiratory distress …
Acetylcysteine (NAC) in patients with COVID19-associated acute respiratory distress …
N-acetylcysteine and coronavirus disease 2019: May it work as a beneficial preventive and adjuvant therapy? A comprehensive review study
Background: Coronaviruses are major pathogens of respiratory system causing different
disorders, including the common cold, Middle East respiratory syndrome, and severe acute …
disorders, including the common cold, Middle East respiratory syndrome, and severe acute …
N-acetylcysteine to combat COVID-19: an evidence review
Z Shi, CA Puyo - Therapeutics and clinical risk management, 2020 - Taylor & Francis
The novel coronavirus disease (COVID-19) is caused by a virus (SARS-Cov-2) and is known
for inducing multisystem organ dysfunction associated with significant morbidity and …
for inducing multisystem organ dysfunction associated with significant morbidity and …
[HTML][HTML] Rationale for the use of N‐acetylcysteine in both prevention and adjuvant therapy of COVID‐19
S De Flora, R Balansky, S La Maestra - The FASEB journal, 2020 - ncbi.nlm.nih.gov
COVID‐19 may cause pneumonia, acute respiratory distress syndrome, cardiovascular
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
alterations, and multiple organ failure, which have been ascribed to a cytokine storm, a …
Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine
H Ibrahim, A Perl, D Smith, T Lewis, Z Kon… - Clinical …, 2020 - Elsevier
Abstract Glucose 6-phosphate dehydrogenase (G6PD) deficiency facilitates human
coronavirus infection due to glutathione depletion. G6PD deficiency may especially …
coronavirus infection due to glutathione depletion. G6PD deficiency may especially …
Double-blind, randomized, placebo-controlled trial with N-acetylcysteine for treatment of severe acute respiratory syndrome caused by coronavirus disease 2019 …
JCG de Alencar, CL Moreira, AD Müller… - Clinical Infectious …, 2021 - academic.oup.com
Background A local increase in angiotensin 2 after inactivation of angiotensin-converting
enzyme 2 by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce a …
enzyme 2 by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may induce a …
Where are we with the use of N-acetylcysteine as a preventive and adjuvant treatment for COVID-19?
F Di Marco, G Foti, AG Corsico - European Review for Medical and …, 2022 - air.unimi.it
OBJECTIVE: As N-acetylcysteine (NAC) is promising as a re-purposed drug for the
adjunctive or supportive treatment of serious COVID-19, this article aimed to describe …
adjunctive or supportive treatment of serious COVID-19, this article aimed to describe …
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