How immunological profile drives clinical phenotype of primary Sjogren's syndrome at diagnosis: analysis of 10,500 patients (Sjogren Big Data Project)
Objective. To evaluate the influence of the main immunological markers on the disease
phenotype at diagnosis in a large international cohort of patients with primary Sjogren's …
phenotype at diagnosis in a large international cohort of patients with primary Sjogren's …
Influence of geolocation and ethnicity on the phenotypic expression of primary Sjögren's syndrome at diagnosis in 8310 patients: a cross-sectional study from the Big …
Objectives To analyse the influence of geolocation and ethnicity on the clinical presentation
of primary Sjögren's syndrome (SjS) at diagnosis. Methods The Big Data Sjögren Project …
of primary Sjögren's syndrome (SjS) at diagnosis. Methods The Big Data Sjögren Project …
Prediction of Sjögren's syndrome years before diagnosis and identification of patients with early onset and severe disease course by autoantibody profiling
E Theander, R Jonsson, B Sjöström… - Arthritis & …, 2015 - Wiley Online Library
Objective Autoantibodies are highly characteristic of primary Sjögren's syndrome (SS) and
represent important tools for studying its pathogenesis. Nonetheless, thus far, no systematic …
represent important tools for studying its pathogenesis. Nonetheless, thus far, no systematic …
Epidemiological profile and north–south gradient driving baseline systemic involvement of primary Sjögren's syndrome
Objective To characterize the systemic phenotype of primary Sjögren's syndrome at
diagnosis by analysing the EULAR-SS disease activity index (ESSDAI) scores. Methods The …
diagnosis by analysing the EULAR-SS disease activity index (ESSDAI) scores. Methods The …
Phenotyping Sjögren's syndrome: towards a personalised management of the disease
P Brito Zeron, MS Retamozo, RC Manuel - 2018 - ri.conicet.gov.ar
Sjögren´ s syndrome (SS) is a systemic autoimmune disease that mainly targets the
exocrine glands. The disease overwhelmingly affects women around 30-60 years old, and …
exocrine glands. The disease overwhelmingly affects women around 30-60 years old, and …
One year in review 2020: comorbidities, diagnosis and treatment of primary Sjogren's syndrome
Primary Sjogren's syndrome (pSS) is a complex and heterogeneous disorder characterised
by a wide spectrum of glandular and extra-glandular features. The discovery of novel …
by a wide spectrum of glandular and extra-glandular features. The discovery of novel …
Systemic manifestations of primary Sjögren's syndrome out of the ESSDAI classification: prevalence and clinical relevance in a large international, multi-ethnic cohort …
S Retamozo, N Acar-Denizli… - Clinical and …, 2019 - discovery.ucl.ac.uk
OBJECTIVES: To analyse the frequency and characterise the systemic presentation of
primary Sjögren's syndrome (SS) out of the ESSDAI classification in a large international …
primary Sjögren's syndrome (SS) out of the ESSDAI classification in a large international …
Symptom-based stratification of patients with primary Sjögren's syndrome: multi-dimensional characterisation of international observational cohorts and reanalyses of …
JR Tarn, N Howard-Tripp, DW Lendrem… - The Lancet …, 2019 - thelancet.com
Background Heterogeneity is a major obstacle to developing effective treatments for patients
with primary Sjögren's syndrome. We aimed to develop a robust method for stratification …
with primary Sjögren's syndrome. We aimed to develop a robust method for stratification …
Unique Sjögren's syndrome patient subsets defined by molecular features
Objective To address heterogeneity complicating primary SS (pSS) clinical trials, research
and care by characterizing and clustering patients by their molecular phenotypes. Methods …
and care by characterizing and clustering patients by their molecular phenotypes. Methods …
Active immunological profile is associated with systemic Sjögren's syndrome
Background The aim of this paper was to study the evolution of primary Sjögren's syndrome
(pSS) immunological profile, its impact on pSS activity and long-term evolution in a bicentric …
(pSS) immunological profile, its impact on pSS activity and long-term evolution in a bicentric …