[HTML][HTML] Seven challenges for neuroscience

H Markram - Functional neurology, 2013 - ncbi.nlm.nih.gov
Although twenty-first century neuroscience is a major scientific enterprise, advances in basic
research have not yet translated into benefits for society. In this paper, I outline seven …

LEMS: a language for expressing complex biological models in concise and hierarchical form and its use in underpinning NeuroML 2

RC Cannon, P Gleeson, S Crook… - Frontiers in …, 2014 - frontiersin.org
Computational models are increasingly important for studying complex neurophysiological
systems. As scientific tools, it is essential that such models can be reproduced and critically …

Arbor: A morphologically detailed neural network simulator for modern high performance computer architectures

W Klijn, S Yates, V Karakasis, A Peyser… - 26th Computational …, 2017 - juser.fz-juelich.de
Arbor is a new multicompartment neural network simulator currently under development as a
collaboration between the Simulation Lab Neuroscience at the Forschungszentrum Jülich …

From clean room to machine room: commissioning of the first-generation BrainScaleS wafer-scale neuromorphic system

H Schmidt, J Montes, A Grübl, M Güttler… - Neuromorphic …, 2023 - iopscience.iop.org
The first-generation of BrainScaleS, also referred to as BrainScaleS-1, is a neuromorphic
system for emulating large-scale networks of spiking neurons. Following a'physical …

Automated reconstruction of neural tissue and the role of large-scale simulation

J Kozloski - Neuroinformatics, 2011 - Springer
The brain implements a myriad of global brain functions to support adaptive behaviors.
Despite their seeming innumerability, these emerge from combinations of lower level …

From biological to numerical experiments in systemic neuroscience: a simulation platform

N Denoyelle, M Carrere, F Pouget, T Viéville… - … and Informatics: Revised …, 2016 - Springer
Studying and modeling the brain as a whole is a real challenge. For such systemic models
(in contrast to models of one brain area or aspect), there is a real need for new tools …

Implementing goal-directed foraging decisions of a simpler nervous system in simulation

JW Brown, D Caetano-Anollés, M Catanho, E Gribkova… - Eneuro, 2018 - eneuro.org
Economic decisions arise from evaluation of alternative actions in contexts of motivation and
memory. In the predatory sea-slug Pleurobranchaea the economic decisions of foraging are …

Towards a bio-inspired real-time neuromorphic cerebellum

PA Bogdan, B Marcinnò, C Casellato… - Frontiers in cellular …, 2021 - frontiersin.org
This work presents the first simulation of a large-scale, bio-physically constrained
cerebellum model performed on neuromorphic hardware. A model containing 97,000 …

From neuromorphic to neurohybrid: transition from the emulation to the integration of neuronal networks

U Bruno, A Mariano, D Rana, T Gemmeke… - Neuromorphic …, 2023 - iopscience.iop.org
The computation of the brain relies on the highly efficient communication among billions of
neurons. Such efficiency derives from the brain's plastic and reconfigurable nature, enabling …

Brainlab: a Python toolkit to aid in the design, simulation, and analysis of spiking neural networks with the NeoCortical Simulator

RP Drewes, Q Zou, PH Goodman - Frontiers in neuroinformatics, 2009 - frontiersin.org
Neuroscience modeling experiments often involve multiple complex neural network and cell
model variants, complex input stimuli and input protocols, followed by complex data …