Sickle cell disease (SCD) is characterized by recurrent vaso-occlusive crisis (VOC). Patients
with SCD have impaired immunity and are thus predispose to infections. The vast majority of …

A homozygous mutation in the gene for β globin, a subunit of adult hemoglobin A (HbA), is
the proximate cause of sickle cell disease (SCD). Sickle hemoglobin (HbS) shows peculiar …

Sickle cell disease (SCD) is characterized by chronic hemolysis, frequent infections, and
recurrent occlusions of microcirculation, which cause painful crises and result in chronic …

The pathogenesis of sickle vaso-occlusive crisis (VOC) in sickle cell disease (SCD) patients
involves the accumulation of rigid sickle cells and the stimulation of an ongoing inflammatory …

Sickle cell disease (SCD) is an hereditary disorder characterized by the production of an
abnormal hemoglobin called hemoglobin S (HbS). HbS may polymerize in deoxygenated …

The aim of our study was to assess the cytokine profile of sickle cell disease (SCD) patients
in steady state and in vaso‐occlusive crisis (VOC). VOC has a complex nature, involving …

Polymorphonuclear leukocyte (PMN) aggregation and chemotaxis were studied in 27
patients with sickle cell disease (SCD). Pain-free patients with SCD had a significantly …

Sickle cell disease (SCD) is an inherited hemoglobinopathy that is caused by the presence
of abnormal hemoglobin S (HbS) in red blood cells, leading to alterations in red cell …

Sickle cell disease (SCD) is characterized by recurrent vaso-occlusive crisis (VOC). VOC is
an important index of disease severity and has been shown to correlate with the risk of multi …

Sickle Cell Anemia (SCA) is the most common genetic disorder around the world. The
mutation in the β-globin gene is responsible for a higher hemolysis rate, with further …