Although it is agreed that physicochemical features of molecules determine their perceived
odor, the rules governing this relationship remain unknown. A significant obstacle to such …

Background Understanding the relationship between a stimulus and how it is perceived
reveals fundamental principles about the mechanisms of sensory perception. While this …

A fundamental problem in systems neuroscience is mapping the physical properties of a
stimulus to perceptual characteristics. In vision, wavelength translates into color; in audition …

To understand the brain mechanisms of olfaction we must understand the rules that govern
the link between odorant structure and odorant perception. Natural odors are in fact mixtures …

Humans share sensory systems with a common anatomical blueprint, but individual sensory
experience nevertheless varies. In olfaction, it is not known to what degree sensory …

In humans, the pleasantness of odors is a major contributor to social relationships and food
intake. Smells evoke attraction and repulsion responses, reflecting the hedonic value of the …

We have developed a new computational framework for merging odor response data sets
from heterogeneous studies, creating a consensus metadatabase, the database of odor …

One major unresolved problem in olfaction research is to relate the percept to the molecular
structure of stimuli. The present study examined this issue and showed for the first time a …

In studies of vision and audition, stimuli can be systematically varied by wavelength and
frequency, respectively, but there is no equivalent metric for olfaction. Restricted odorant …

The main problem with sensory processing is the difficulty in relating sensory input to
physiological responses and perception. This is especially problematic at higher levels of …