Mitochondrial calcium handling is a particularly active research area in the neuroscience
field, as it plays key roles in the regulation of several functions of the central nervous system …

Mitochondria efficiently buffer Ca 2+ influx during excitation, which limits the amplitude of
cytosolic Ca 2+ rise, and then slowly release Ca 2+ back into the cytosol thereby extending …

Mitochondria play a pivotal role in intracellular Ca2+ signalling by taking up and releasing
the ion upon specific conditions. In order to do so, mitochondria depend on a number of …

Mitochondrial Ca2+ plays a critical role in controlling cytosolic Ca2+ buffering, energy
metabolism, and cellular signal transduction. Overloading of mitochondrial Ca2+ contributes …

Mitochondria are involved in a large number of essential roles related to neuronal function.
Ca 2+ handling by mitochondria is critical for many of these functions, including energy …

Ca2+ handling by mitochondria is a critical function regulating both physiological and
pathophysiological processes in a broad spectrum of cells. The ability to accurately measure …

While neuronal mitochondria have been studied extensively in their role in health and
disease, the rules that govern calcium regulation in mitochondria remain somewhat vague …

Mitochondria are essential for proper cellular function through their critical roles in ATP
synthesis, reactive oxygen species production, calcium (Ca2+) buffering, and apoptotic …

Mitochondrial Ca 2+ plays a critical physiological role in cellular energy metabolism and
signaling, and its overload contributes to various pathological conditions including neuronal …

Calcium handling by mitochondria is a key feature in cell life. It is involved in energy
production for cell activity, in buffering and shaping cytosolic calcium rises and also in …