Lipid coverage is crucial in comprehensive lipidomics studies challenged by high diversity in
lipid structures and wide dynamic range in lipid levels. Current state-of-the-art lipidomics …

Lipidomics is a critical part of metabolomics and aims to study all the lipids within a living
system. We present here the development and evaluation of a sensitive capillary UPLC-MS …

Liquid chromatography–mass spectrometry (LC–MS) methods are most often used for
untargeted metabolomics and lipidomics. However, methods have not been standardized as …

The goal of untargeted lipidomics is to have high throughput, yet comprehensive and
unambiguous identification and quantification of lipids. Novel stationary phases in LC …

Lipids are vital biological molecules and play multiple roles in cellular function of
mammalian organisms such as cellular membrane anchoring, signal transduction, material …

Exploratory or untargeted ultra performance liquid chromatography–mass spectrometry
(UPLC–MS) profiling offers an overview of the complex lipid species diversity present in …

Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid
metabolic pathways involved in many (patho) physiological events. Targeted and non …

Lipids are important biomolecules in all biological systems and serve numerous essential
cellular functions. The global analysis of complex lipids is very challenging due to the …

Untargeted lipidomics using liquid chromatography (LC) coupled with tandem mass
spectrometry (MS) is essential for large cohort studies. Using a fast LC gradient of less than …

Lipids, serving as the structural components of cellular membranes, energy storage, and
signaling molecules, play the essential and multiple roles in biological functions of …