The mechanism of peritoneal fibrosis in patients on continuous ambulatory peritoneal
dialysis (CAPD) is poorly elucidated. We investigated the cellular mechanism of high …

High glucose induces MCP-1 expression partly via tyrosine kinase–AP-1 pathway in
peritoneal mesothelial cells. Background High glucose in peritoneal dialysis solutions has …

Background Bacterial peritonitis is one of the most frequent complications in patients on
peritoneal dialysis. In the present study, we investigated effects of peritoneal dialysis fluid …

Background Peritoneal fibrosis is a serious complication of long-term peritoneal dialysis,
and yet the precise pathogenic mechanisms of peritoneal fibrosis remain unknown …

High glucose activates the p38 MAPK pathway in cultured human peritoneal mesothelial
cells. Background Peritoneal fibrosis is a serious complication in long-term continuous …

Epithelial–mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs) has a role
in the process of peritoneal fibrosis (PF), a serious complication in peritoneal dialysis (PD) …

High glucose–induced PKC activation mediates TGF-β1 and fibronectin synthesis by
peritoneal mesothelial cells. Background Progressive peritoneal fibrosis, membrane …

Peritoneal fibrosis (PF) is an irreversible complication of peritoneal dialysis (PD) that leads
to loss of peritoneal membrane function. We investigated PD effluent and serum levels and …

Background Bacterial peritonitis is a frequent complication in patients on peritoneal dialysis
(PD). We previously reported that PD fluid (PDF) suppressed expression of monocyte …

Peritoneal fibrosis (PF) is an important complication of long-term peritoneal dialysis.
Although mineralocorticoid and mineralocorticoid receptor (MR) have attracted increasing …