Towards the construction of avian chromosome assemblies

J Damas, M Farré, P Lithgow, MN Romanov… - Chromosome …, 2015 - kar.kent.ac.uk
The advent of the next generation sequencing (NGS) made sequencing and scaffolding of
an entire animal genome a routine procedure. As the result we face a fast increase in the …

In silico reconstruction of chromosomal rearrangements and an avian ancestral karyotype

MN Romanov, M Farré-Belmonte, PE Lithgow… - 2014 - kar.kent.ac.uk
The recent availability of whole genome assemblies for multiple bird species has changed
the way we can detect and describe patterns of avian genome evolution. Coupled with …

Assembling and comparing avian genomes by molecular cytogenetics

H Martell, R O'Connor, J Damas, A Mandawala… - 2015 - kar.kent.ac.uk
There has been a recent explosion in avian genomics. In December 2014 the Beijing
Genomics Institute in collaboration with a number of labs worldwide (including Kent) …

Upgrading short-read animal genome assemblies to chromosome level using comparative genomics and a universal probe set

J Damas, R O'Connor, M Farré, VPE Lenis… - Genome …, 2017 - genome.cshlp.org
Most recent initiatives to sequence and assemble new species' genomes de novo fail to
achieve the ultimate endpoint to produce contigs, each representing one whole …

New approaches for genome assembly and scaffolding

ES Rice, RE Green - Annual review of animal biosciences, 2019 - annualreviews.org
Affordable, high-throughput DNA sequencing has accelerated the pace of genome
assembly over the past decade. Genome assemblies from high-throughput, short-read …

Avian ancestral karyotype reconstruction and differential rates of inter-and intra-chromosomal change in different lineages

MN Romanov, M Farré, PE Lithgow… - Chromosome …, 2015 - kar.kent.ac.uk
In birds, genome is organised into several large chromosomes (macrochromosomes) and
many smaller chromosomes (microchromosomes) that usually constitute about 25 and 75 …

Reference-assisted chromosome assembly

J Kim, DM Larkin, Q Cai, Asan… - Proceedings of the …, 2013 - National Acad Sciences
One of the most difficult problems in modern genomics is the assembly of full-length
chromosomes using next generation sequencing (NGS) data. To address this problem, we …

Avian cytogenetics goes functional

DK Griffin, M Farré, P Lithgow, R O'Connor… - Chromosome …, 2014 - kar.kent.ac.uk
Whole chromosomes (and sub-chromosomal homologous synteny blocks (HSBs)) have
great significance in molecular studies of genome evolution. In birds, our ability to define …

Reconstruction of avian ancestral karyotypes reveals differences in the evolutionary history of macro-and microchromosomes

J Damas, J Kim, M Farré, DK Griffin, DM Larkin - Genome biology, 2018 - Springer
Background Reconstruction of ancestral karyotypes is critical for our understanding of
genome evolution, allowing for the identification of the gross changes that shaped extant …

Sequencing the bovine genome

KC Worley, RA Gibbs - Bovine Genomics, 2012 - Wiley Online Library
The large project of sequencing and assembly of the bovine genome leveraged the many
resources available and provided the pivotal substrate for research in the future. The …