[PDF][PDF] American Journal of Current Microbiology

H Zhang - 2021 - core.ac.uk
The recent outbreak of the COVID-19 pandemic has spread from China to the rest of the
world in part because the virus has a high infection rate. The lack of a vaccine and …

[HTML][HTML] Network bioinformatics analysis provides insight into drug repurposing for COVID-19

X Li, J Yu, Z Zhang, J Ren, AE Peluffo, W Zhang… - Medicine in Drug …, 2021 - Elsevier
The COVID-19 disease caused by the SARS-CoV-2 virus is a health crisis worldwide. While
developing novel drugs and vaccines is long, repurposing existing drugs against COVID-19 …

An Omics Strategy for Translational Bioinformatics and Rapid COVID-19 Drug Repurposing

A Revikumar - OMICS: A Journal of Integrative Biology, 2023 - liebertpub.com
As COVID-19 continues to evolve around the world, there are unmet needs for rapid
discovery, repurposing, and development of antiviral drugs. COVID-19 drug development is …

Multi-omics data integration and network-based analysis drives a multiplex drug repurposing approach to a shortlist of candidate drugs against COVID-19

M Tomazou, MM Bourdakou, G Minadakis… - Briefings in …, 2021 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic is
undeniably the most severe global health emergency since the 1918 Influenza outbreak …

Comparative transcriptome analysis of SARS-CoV, MERS-CoV, and SARS-CoV-2 to identify potential pathways for drug repurposing

P Krishnamoorthy, AS Raj, S Roy, NS Kumar… - Computers in biology …, 2021 - Elsevier
The ongoing COVID-19 pandemic caused by the coronavirus, SARS-CoV-2, has already
caused in excess of 1.25 million deaths worldwide, and the number is increasing …

Repurposing FDA-approved drugs for COVID-19 using a data-driven approach

RRR Duarte, DC Copertino Jr, LP Iñiguez, JL Marston… - 2020 - chemrxiv.org
There have been more than 116,000 recorded deaths worldwide to-date caused by the
severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2), the etiological agent …

Identification of 37 heterogeneous drug candidates for treatment of COVID-19 via a rational transcriptomics-based drug repurposing approach

A Gelemanović, T Vidović, V Stepanić, K Trajković - Pharmaceuticals, 2021 - mdpi.com
A year after the initial outbreak, the COVID-19 pandemic caused by SARS-CoV-2 virus
remains a serious threat to global health, while current treatment options are insufficient to …

[HTML][HTML] A Comprehensive SARS-CoV-2 Genomic Analysis Identifies Potential Targets for Drug Repurposing

AK Pradhan, N Tayal, A Bansal, S Donakonda… - 2020 - europepmc.org
Background: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) which is
a novel human coronavirus strain (HCoV) initially reported in December 2019 in Wuhan …

A connectivity map-based drug repurposing study and integrative analysis of transcriptomic profiling of SARS-CoV-2 infection

SZ Mousavi, M Rahmanian, A Sami - Infection, Genetics and Evolution, 2020 - Elsevier
Aims The recent outbreak of COVID-19 has become a global health concern. There are
currently no effective treatment strategies and vaccines for the treatment or prevention of this …

Data-driven drug repurposing for COVID-19

R Mall, A Elbasir, H Al Meer, S Chawla, E Ullah - 2020 - chemrxiv.org
Motivation: A global effort is underway to identify drugs for the treatment of COVID-19. Since
de novo drug design is an extremely long, time-consuming, and expensive process, efforts …