J Majewski, DW Schultz, RG Weleber… - The American Journal of …, 2003 - cell.com
We performed a genomewide scan and genetic linkage analysis, to identify loci associated with age-related macular degeneration (AMD). We collected 70 families, ranging from small …
SA Fisher, GR Abecasis, BM Yashar… - Human molecular …, 2005 - academic.oup.com
A genetic contribution to the development of age-related macular degeneration (AMD) is well established. Several genome-wide linkage studies have identified a number of putative …
JM Seddon, SL Santangelo, K Book, S Chong… - The American Journal of …, 2003 - cell.com
We report the results of a genomewide scan for age-related macular degeneration (AMD) in 158 multiplex families. AMD classification was based on fundus photography and was …
Family-and population-based genetic studies have successfully identified multiple disease- susceptibility loci for Age-related macular degeneration (AMD), one of the first batch and …
SK Iyengar, D Song, BEK Klein, R Klein… - The American Journal of …, 2004 - cell.com
To examine the genetic basis of age-related macular degeneration (ARMD), a degenerative disease of the retinal pigment epithelium and neurosensory retina, we conducted a …
Importance Rare variants in the complement genesCFH, CFI, C9, andC3have been found to be highly associated with age-related macular degeneration (AMD); however, the effect on …
MB Gorin - Molecular aspects of medicine, 2012 - Elsevier
Age-related macular degeneration (AMD) is a common condition among the elderly population that leads to the progressive central vision loss and serious compromise of …
ML Klein, DW Schultz, A Edwards… - Archives of …, 1998 - jamanetwork.com
Objectives To identify the chromosomal location of a disease-causing gene and to describe the clinical characteristics of a large family with age-related macular degeneration (ARMD) …