Anatomical and physiological plasticity of dendritic spines

VA Alvarez, BL Sabatini - Annu. Rev. Neurosci., 2007 - annualreviews.org
In excitatory neurons, most glutamatergic synapses are made on the heads of dendritic
spines, each of which houses the postsynaptic terminal of a single glutamatergic synapse …

Dendritic spine plasticity: looking beyond development

KJ Harms, A Dunaevsky - Brain research, 2007 - Elsevier
Most excitatory synapses in the CNS form on dendritic spines, tiny protrusions from the
dendrites of excitatory neurons. As such, spines are likely loci of synaptic plasticity. Spines …

Spine plasticity in the motor cortex

X Yu, Y Zuo - Current opinion in neurobiology, 2011 - Elsevier
Dendritic spines are the postsynaptic sites of the majority of excitatory synapses in the
mammalian central nervous system. The morphology and dynamics of dendritic spines …

Dendritic spine plasticity: function and mechanisms

K Runge, C Cardoso, A De Chevigny - Frontiers in synaptic …, 2020 - frontiersin.org
Dendritic spines are small protrusions studding neuronal dendrites, first described in 1888
by Ramón y Cajal using his famous Golgi stainings. Around 50 years later the advance of …

Dendritic spine morphogenesis and plasticity

J Lippman, A Dunaevsky - Journal of neurobiology, 2005 - Wiley Online Library
Dendritic spines are small protrusions off the dendrite that receive excitatory synaptic input.
Spines vary in size, likely correlating with the strength of the synapses they form. In the …

Examining form and function of dendritic spines

KFH Lee, C Soares, JC Béïque - Neural plasticity, 2012 - Wiley Online Library
The majority of fast excitatory synaptic transmission in the central nervous system takes
place at protrusions along dendrites called spines. Dendritic spines are highly …

Dentritic spines: structure, dynamics and regulation

H Hering, M Sheng - Nature Reviews Neuroscience, 2001 - nature.com
Dendritic spines are tiny protrusions that receive excitatory synaptic input and
compartmentalize postsynaptic responses. Heterogeneous in size and shape, and …

Dendritic spine plasticity—current understanding from in vivo studies

G Knott, A Holtmaat - Brain research reviews, 2008 - Elsevier
Changes in sensory experience modify the function of the adult brain's neuronal circuits.
This flexibility is reliant on the neurons' ability to change the strength of their connections …

Structure and function of dendritic spines

EA Nimchinsky, BL Sabatini… - Annual review of …, 2002 - annualreviews.org
▪ Abstract Spines are neuronal protrusions, each of which receives input typically from one
excitatory synapse. They contain neurotransmitter receptors, organelles, and signaling …

Structural dynamics of dendritic spines in memory and cognition

H Kasai, M Fukuda, S Watanabe… - Trends in …, 2010 - cell.com
Recent studies show that dendritic spines are dynamic structures. Their rapid creation,
destruction and shape-changing are essential for short-and long-term plasticity at excitatory …