Critical role of estrogen in the progression of chronic liver diseases

D Ezhilarasan - Hepatobiliary & Pancreatic Diseases International, 2020 - Elsevier
Background Estrogens regulate sexual function and also have a significant role in various
pathophysiological processes. Estrogens have a non-reproductive role as the modulators of …

[HTML][HTML] Female hepatology: favorable role of estrogen in chronic liver disease with hepatitis B virus infection

I Shimizu, N Kohno, K Tamaki, M Shono… - World Journal of …, 2007 - ncbi.nlm.nih.gov
Chronic hepatitis B virus (HBV) infection is the most common cause of hepatic fibrosis and
hepatocellular carcinoma (HCC), mainly as a result of chronic necroinflammatory liver …

Impact of oestrogens on the progression of liver disease

I Shimizu - Liver International, 2003 - Wiley Online Library
As of this writing, the most common cause of hepatic fibrosis is chronic hepatitis C virus
infection (HCV), the characteristic feature of which is hepatic steatosis. Hepatic steatosis …

Protection of estrogens against the progression of chronic liver disease

I Shimizu, S Ito - Hepatology Research, 2007 - Wiley Online Library
Hepatitis C virus infections are recognized as a major causative factor of chronic liver
disease. A characteristic feature of chronic hepatitis C, alcoholic liver disease and non …

Non-alcoholic fatty liver disease as a canonical example of metabolic inflammatory-based liver disease showing a sex-specific prevalence: relevance of estrogen …

S Della Torre - Frontiers in endocrinology, 2020 - frontiersin.org
There is extensive evidence supporting the interplay between metabolism and immune
response, that have evolved in close relationship, sharing regulatory molecules and …

Role of estrogens in the regulation of liver lipid metabolism

BT Palmisano, L Zhu, JM Stafford - Sex and gender factors affecting …, 2017 - Springer
Before menopause, women are protected from atherosclerotic heart disease associated with
obesity relative to men. Sex hormones have been proposed as a mechanism that …

[HTML][HTML] Liver disease in menopause

CW Brady - World Journal of Gastroenterology: WJG, 2015 - ncbi.nlm.nih.gov
There are numerous physiologic and biochemical changes in menopause that can affect the
function of the liver and mediate the development of liver disease. Menopause represents a …

Sex hormones and their receptors regulate liver energy homeostasis

M Shen, H Shi - International journal of endocrinology, 2015 - Wiley Online Library
The liver is one of the most essential organs involved in the regulation of energy
homeostasis. Hepatic steatosis, a major manifestation of metabolic syndrome, is associated …

[HTML][HTML] Estrogen receptor expression in chronic hepatitis C and hepatocellular carcinoma pathogenesis

JK Iyer, M Kalra, A Kaul, ME Payton… - World journal of …, 2017 - ncbi.nlm.nih.gov
AIM To investigate gender-specific liver estrogen receptor (ER) expression in normal
subjects and patients with hepatitis C virus (HCV)-related cirrhosis and hepatocellular …

Estrogen deficiency worsens steatohepatitis in mice fed high-fat and high-cholesterol diet

Y Kamada, S Kiso, Y Yoshida… - American Journal …, 2011 - journals.physiology.org
Recent studies indicate an accelerated progression of nonalcoholic steatohepatitis (NASH)
in postmenopausal women. Hypercholesterolemia, an important risk factor for NASH …