Lipidomic approaches are now widely used to investigate the relationship between lipid
metabolism, health and disease. Large-scale lipidomics studies typically aim to quantify …

In recent years, high-throughput lipid profiling has contributed to understand the biological,
physiological and pathological roles of lipids in living organisms. Across all kingdoms of life …

Liquid chromatography-mass spectrometry (LC-MS)-based lipidomics has undergone
dramatic developments over the past decade. This review focuses on state of the art in LC …

Over the last decade, technological advances have improved the sensitivity and selectivity of
LC/MS analyzers, providing very efficient tools for lipidomics research. In particular, the nine …

The state-of-art in the lipidomic analysis is summarized here to provide the overview of
available sample preparation strategies, mass spectrometry (MS)-based methods for the …

Lipids play a key role in the signaling pathways of cancer, cardiovascular, diabetic, and
inflammatory diseases. A major challenge in the analysis of lipids is the many isobaric …

The objective of this review is to provide a comprehensive summary of the latest
methodological advancements and emerging patterns in utilizing lipidomics in clinical …

Lipids are amongst the most important organic compounds in living organisms, where they
serve as building blocks for cellular membranes as well as energy storage and signaling …

Highlights•The extreme diversity of the lipidome poses a significant analytical challenge.•A
variety of mass spectrometry-based approaches exist for the analysis of lipids.•Combining …

Lipids have been analyzed in applications including drug discovery, disease etiology
elucidation, and natural products. The chemical and structural diversity of lipids requires a …