Heart transplantation became a reality at the end of the 1960s as a life-saving option for
patients with end-stage heart failure. Static cold storage (SCS) at 4–6° C has remained the …

Heart disease remains a leading cause of mortality throughout the world. Mammals have an
extremely limited capacity to repair lost or damaged heart tissue, thus encouraging …

Cardiovascular disease is the leading cause of death worldwide. Compared to other organs
such as the liver, the adult human heart lacks the capacity to regenerate on a macroscopic …

While humans lack sufficient capacity to undergo cardiac regeneration following injury,
zebrafish can fully recover from a range of cardiac insults. Over the past two decades, our …

In humans, myocardial infarction results in ventricular remodeling, progressing ultimately to
cardiac failure, one of the leading causes of death worldwide. In contrast to the adult …

The adult mammalian heart has an extremely limited capacity for regeneration. As a
consequence, ischemic heart disease remains the leading cause of death in the developed …

Cardiovascular diseases are one of the leading causes of death globally. The primary
pathological mechanism in myocardial infarction and heart failure is irreversible …

Heart failure caused by cardiomyocyte loss after ischemic tissue damage is a leading cause
of death worldwide. Although adult mammalian cardiomyocytes are able to proliferate during …

Cardiovascular disease is the leading cause of death in the US and worldwide. Failure to
properly repair or regenerate damaged cardiac tissues after myocardial infarction is a major …

Regeneration is a complex biological process by which animals can restore the shape,
structure and function of body parts lost after injury, or after experimental amputation. Only a …