The essential Aurora B kinase is a chromosomal passenger protein that is required for
mitotic chromosome alignment and segregation. Aurora B function is dependent on the …

A family of serine/threonine kinase Aurora constitutes a key regulator in the orchestration of
mitotic events. The human Aurora paralogues Aurora-A, Aurora-B, and Aurora-C have a …

The function of Aurora‐C kinase, a member of the Aurora kinase family identified in
mammals, is currently unknown. We present evidence that Aurora‐C, like Aurora‐B kinase …

Aurora kinases are emerging as key regulators of centrosome function, chromosome
segregation and cytokinesis. We previously isolated Aurora-C (Aie1), a third type of Aurora …

Mitotic kinases regulate cell division and its checkpoints, errors of which can lead to
aneuploidy or genetic instability. One of these is Aurora-B, a key kinase that is required for …

Aurora B is a mitotic protein kinase that phosphorylates histone H3, behaves as a
chromosomal passenger protein, and functions in cytokinesis. We investigated a role for …

Aurora B kinase has a critical role in regulating attachments between kinetochores and
spindle microtubules during mitosis. Early in mitosis, kinase activity at kinetochores is high to …

Abstract The Aurora (Ipl1)-related kinases are universal regulators of mitosis. We now show
that Aurora-A, in addition to Aurora-B, regulates kinetochore function in human cells. A two …

The function of the Aurora B kinase at centromeres and the central spindle is crucial for
chromosome segregation and cytokinesis, respectively. Herein, we have investigated the …

How the events of mitosis are coordinated is not well understood. Intriguing mitotic
regulators include the chromosomal passenger proteins. Loss of either of the passengers …