Background: The platelet count, prothrombin time (PT), activated partial thromboplastin time
(APTT) and D-dimer levels of patients with sickle cell disease (SCD) in steady state (32 …

Background: There is increasing evidence suggesting the contribution of platelets in the
vaso-occlusive phenomena found in sickle cell anaemia. This study is aimed at using …

Background: Sickle cell disease (SCD) is a hereditary haemoglobinopathy characterized by
deranged haematopoiesis, and intermittent occlusion of small blood vessels. Patients can …

Background: The evidence from various studies showed that patients with sickle cell disease
(SCD) have altered components of hemostasis such as platelet function, procoagulant …

Background: Sickle cell anaemia (SCA) is a major cause of morbidity and mortality in Africa
where there is no readily available effective treatment. This study was designed to determine …

Abstract Background/Aim: Painful vaso-occlusive crisis (VOC) is the most frequent
complication of sickle cell disease. The cause of VOC is believed to be ischemic tissue injury …

Background: Sickle cell disease (SCD) is considered to be a hypercoagulable state that
contributes to the morbidity associated with the disease. Numerous mechanisms can …

Aims: The purpose of this research was to assess and compare the coagulation and
haematological profiles of sickle cell disease (SCD) patients to those without the condition …

Background: Reports from various studies showed that patients with sickle cell anemia
(SCA) have altered components of hemostasis such as platelet function, the procoagulant …

One hundred patients with sickle cell anaemia (SCA) in steady state within the ages of 1-30
years were studied with respect to haematocrit and platelet count. The same number of age …