Background: Sickle cell disease (SCD) is a disorder marked by a single-point mutation in the
beta-globin gene. Hydroxyurea is a globally accepted disease-modifying agent that sounds …

ABSTRACT Introduction: Sickle Cell Disease (SCD) is an autosomal recessive multisystem
disorder, characterised by anaemia, recurrent episodes of pain and chronic organ damage …

Background: Sickle cell disease (SCD) is a prevalent hemoglobinopathy involving sickled
hemoglobin that causes multiorgan disease due to chronic recurrent vaso-occlusion and …

Sickle cell disease (SCD) is a group of inherited disorders of hemoglobin synthesis. It is
prevalent in different parts of the world, including the Kingdom of Saudi Arabia. The disease …

Sickle cell disease (SCD) is common in tribal belt of Gujarat, but not addressed effectively as
it should be with effective use of Hydroxyurea, supportive care and counseling. In our single …

Objective: The aim of this study was to determine the effect of hydroxyurea on adverse
clinical events and haematological indices in paediatric patients with sickle cell anaemia …

Background Sickle cell disease (SCD) is an autosomal recessive hemoglobinopathy that is
very common and causes a great burden in Saudi Arabia and worldwide. This study aims to …

Background: The clinical prospects of hydroxyurea therapy in the management of sickle cell
disease (SCD) require evaluation in the Nigerian setting to develop indigenous guidelines …

Background Sickle cell disease (SCD) is a hereditary disorder marked by abnormal
hemoglobin (HbS), leading to chronic hemolytic anemia, vaso-occlusive crises (VOCs), and …

Background In Saudi Arabia, sickle cell disease (SCD) is a major public health issue,
especially in the eastern region. Sickle cell patients have major health-related issues …