Rationale Mobile‐phase additives in liquid chromatography/mass spectrometry (LC/MS) are
used to improve peak shape, analyte ionization efficiency and method coverage. Both basic …

Reversed-phase ultrahigh-performance liquid chromatography–mass spectrometry (UHPLC–
MS) is the method of choice for lipidomic profiling of blood plasma. For comprehensive …

Orthogonal separation techniques coupled to high-resolution mass spectrometry are
required for characterizing the human lipidome, given its inherent chemical and structural …

In the past decade, many new strategies for mass spectrometry (MS)-based analyses of
lipids have been developed. Lipidomics is one of the most promising research fields to …

Mass spectrometric analysis of cellular lipids is an enabling technology for lipidomics, which
is a rapidly-developing research field. In this review, we briefly discuss the principles …

Recent advances in mass spectrometry have expanded our knowledge of lipids and lipid
metabolic pathways involved in many (patho) physiological events. Targeted and non …

A lipidomics strategy, combining high resolution reversed-phase liquid chromatography
(RPLC) with high resolution quadrupole time-of-flight mass spectrometry (QqTOF), is …

Lipidomics is rapidly expanding because of the great facilitation of recent advances in, and
novel applications of, electrospray ionization mass spectrometry techniques. The greatest …

The goal of untargeted lipidomics is to have high throughput, yet comprehensive and
unambiguous identification and quantification of lipids. Novel stationary phases in LC …

The essence of shotgun lipidomics is to maintain consistency of the chemical environment of
lipid samples during mass spectrometry acquisition. This strategy is suitable for large-scale …