A multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination versus amlodipine in patients with mild to moderate hypertension

P Palatini, E Malacco, R Fogari, R Carretta… - Journal of …, 2001 - journals.lww.com
A multicenter, randomized double-blind study of valsartan/hy... : Journal of Hypertension A
multicenter, randomized double-blind study of valsartan/hydrochlorothiazide combination …

Amlodipine/valsartan/hydrochlorothiazide: fixed-dose combination in hypertension

ED Deeks - American journal of cardiovascular drugs, 2009 - Springer
Abstract▲ Amlodipine/valsartan/hydrochlorothiazide (HCTZ) is a fixed-dose combination of
the well established antihypertensive agents amlodipine (a calcium channel antagonist) …

Efficacy and tolerability of the combination valsartan/hydrochlorothiazide compared with amlodipine in a mild‐to‐moderately hypertensive Brazilian population

RJS Franco, S Goldflus, M Mcquitty, W Oigman… - Blood …, 2003 - Taylor & Francis
Most hypertensive patients need more than one drug to reach recommended blood‐
pressure targets. We investigated the effects on 24‐h ambulatory blood pressure (ABP) of …

Triple antihypertensive therapy with amlodipine, valsartan, and hydrochlorothiazide: a randomized clinical trial

DA Calhoun, Y Lacourciere, YT Chiang, RD Glazer - Hypertension, 2009 - Am Heart Assoc
Many patients with hypertension require≥ 3 agents to achieve target blood pressure (BP).
The efficacy/safety of the dual combinations of valsartan (Val)/hydrochlorothiazide (HCTZ) …

Valsartan–amlodipine–hydrochlorothiazide: the definitive fixed combination?

V Barrios, C Escobar - Expert Review of Cardiovascular Therapy, 2010 - Taylor & Francis
A significant proportion of patients with hypertension will need three or more
antihypertensive agents to achieve blood pressure goals, particularly those at higher risk …

Efficacy and tolerability of valsartan in combination with hydrochlorothiazide in essential hypertension

W Dallas Hall, R Montoro, T Littlejohn, A Jain… - Clinical drug …, 1998 - Springer
Objective: This study compared the efficacy and tolerability of two combination regimens of
valsartan and hydrochlorothiazide (HCTZ) with valsartan monotherapy in patients with …

Combination therapy with valsartan/hydrochlorothiazide at doses up to 320/25 mg improves blood pressure levels in patients with hypertension inadequately …

J Tuomilehto, A Tykarski, P Baumgart, B Reimund… - Blood …, 2008 - Taylor & Francis
Objectives. To investigate the efficacy and tolerability of valsartan (Val) 320 mg once daily
(od), Val/hydrochlorothiazide (HCTZ) 320/12.5 mg od and Val/HCTZ 320/25 mg od in …

Valsartan/hydrochlorothiazide: pharmacology and clinical efficacy

R Kondrack, S Mohiuddin - Expert opinion on drug metabolism & …, 2009 - Taylor & Francis
Background: Valsartan/hydrochlorothiazide is a combination of an angiotensin II receptor
antagonist and diuretic indicated for hypertensive patients as initial therapy and those not …

Valsartan and hydrochlorothiazide in patients with essential hypertension. A multiple dose, double-blind, placebo controlled trial comparing combination therapy with …

JR Benz, HR Black, A Graff, A Reed… - Journal of human …, 1998 - nature.com
Objective: This study compares the antihypertensive efficacy and tolerability of valsartan, a
novel angiotensin II antagonist, given with hydrochlorothiazide (HCTZ) vs placebo or vs …

Achieving blood pressure goal: initial therapy with valsartan/hydrochlorothiazide combination compared with monotherapy

MH Weinberger, RD Glazer, NA Crikelair… - Journal of human …, 2010 - nature.com
The benefits of valsartan (Val)/hydrochlorothiazide (HCTZ) combination as initial treatment
for hypertension were evaluated in a post hoc analysis of an 8-week, double-blind, placebo …