Direct comparison of different therapeutic cell types susceptibility to inflammatory cytokines associated with COVID-19 acute lung injury

R Vaka, S Khan, B Ye, Y Risha, S Parent… - Stem Cell Research & …, 2022 - Springer
Background Although 90% of infections with the novel coronavirus 2 (COVID-19) are mild,
many patients progress to acute respiratory distress syndrome (ARDS) which carries a high …

Stem Cell‐based therapies for COVID‐19‐related acute respiratory distress syndrome

HW Ngai, DH Kim, M Hammad… - Journal of Cellular …, 2022 - Wiley Online Library
As the number of confirmed cases and resulting death toll of the COVID‐19 pandemic
continue to increase around the globe‐especially with the emergence of new mutations of …

Immunomodulatory therapeutic potential of mesenchymal stem cells in COVID-19 pathogenesis

K Singh, A Kumar - Stem Cells, 2024 - Elsevier
Immunomodulatory therapeutic approaches such as glucocorticoid therapy, convalescent
plasma therapy, and antiinterleukin (IL-6) receptor antibody therapy have been used for the …

pcMSC modulates immune dysregulation in patients with COVID-19-induced refractory acute lung injury

MC Chen, KSL Lai, KL Chien, ST Teng, YR Lin… - Frontiers in …, 2022 - frontiersin.org
Background and Objectives The novel coronavirus disease 2019 (COVID-19) has been a
pandemic health issue in 30 January 2020. The mortality rate is as high as 50% in critically …

The rationale of using mesenchymal stem cells in patients with COVID-19-related acute respiratory distress syndrome: What to expect

A Can, H Coskun - Stem Cells Translational Medicine, 2020 - academic.oup.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)-caused coronavirus
disease 2019 (COVID-19) pandemic has become a global health crisis with an extremely …

Cell-based therapy to reduce mortality from COVID-19: Systematic review and meta-analysis of human studies on acute respiratory distress syndrome

W Qu, Z Wang, JM Hare, G Bu… - Stem Cells …, 2020 - academic.oup.com
Severe cases of COVID-19 infection, often leading to death, have been associated with
variants of acute respiratory distress syndrome (ARDS). Cell therapy with mesenchymal …

Therapeutic mechanisms of mesenchymal stem cells in acute respiratory distress syndrome reveal potentials for Covid-19 treatment

W Wang, W Lei, L Jiang, S Gao, S Hu, ZG Zhao… - Journal of Translational …, 2021 - Springer
The mortality rate of critically ill patients with acute respiratory distress syndrome (ARDS) is
30.9% to 46.1%. The emergence of the coronavirus disease 2019 (Covid-19) has become a …

Focusing on the cytokine storm in the battle against COVID-19: the rising role of mesenchymal-derived stem cells

A Naeem, A Waseem, AJ Siddiqui, B Ray, R Sinha… - Stem Cells, 2024 - Elsevier
A worldwide pandemic known as coronavirus disease-19 (COVID-19) has caused various
clinical complications, ranging from carriers without symptoms to acute respiratory distress …

Bone marrow-derived mesenchymal stromal cell therapy in severe COVID-19: preliminary results of a phase I/II clinical trial

C Grégoire, N Layios, B Lambermont… - Frontiers in …, 2022 - frontiersin.org
Background Treatment of acute respiratory distress syndrome (ARDS) associated with
COronaVIrus Disease-2019 (COVID-19) currently relies on dexamethasone and supportive …

Allogenic mesenchymal stromal cells and their extracellular vesicles in COVID-19 induced ARDS: A randomized controlled trial

M Zarrabi, MA Shahrbaf, M Nouri, F Shekari… - Stem Cell Research & …, 2023 - Springer
Background and aims The main causes of death in patients with severe Coronavirus
disease-2019 (COVID-19) are acute respiratory distress syndrome (ARDS) and multiorgan …